false positive

[yolanda...@gmail.com]

Dear Zheng Xia,
I'm trying to use DaPars for detecting APA site usage of my RNA-Seq data.
I succeed in running the tool, got dozens to hundreds pass-filter events for each 2 sample comparison.
However I found high false positive rate in the result. Many pass-filter events can not be verified by checking IGV figures, or checking by q-PCR.
Therefore, I would like to try the "Non-uniformity correction" method stated on your Nature Com paper.
I can not find the way. Seems not include in the code (DaPars v0.9.1)?
Would you please advice how to do it? Or do you have other suggestion to reduce false positive?

Thanks and regards,

Liu Yang
Cancer Science Institute
Singapore