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Abby Williams
,
Ryan Gutenkunst
2
Sep 6
Comparing non-nested models with linked SNPs
Hello Abby, I'm sorry I don't have a very satisfying answer. My group's approach is
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Comparing non-nested models with linked SNPs
Hello Abby, I'm sorry I don't have a very satisfying answer. My group's approach is
Sep 6
Gutenkunst, Ryan N - (rgutenk)
Aug 25
Other:GenomicHistory.Inference.StrategiesTournament
Hello dadi users! The 2025 Genomic History Inference Strategies Tournament (GHIST) is live at https:/
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Other:GenomicHistory.Inference.StrategiesTournament
Hello dadi users! The 2025 Genomic History Inference Strategies Tournament (GHIST) is live at https:/
Aug 25
Skye Davis
,
Ryan Gutenkunst
2
Aug 17
Understanding LRT
Hello Skye, No apologies needed. This is generally confusing. :-) For symmetric versus asymmetric
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Understanding LRT
Hello Skye, No apologies needed. This is generally confusing. :-) For symmetric versus asymmetric
Aug 17
Emma Howell
,
Ryan Gutenkunst
2
Jul 31
Testing for distinct marginal DFEs in a joint DFE context
Hello Emma, Sorry for the slow reply. This is a subtle issue, and I don't think we have a great
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Testing for distinct marginal DFEs in a joint DFE context
Hello Emma, Sorry for the slow reply. This is a subtle issue, and I don't think we have a great
Jul 31
Ryan Gutenkunst
Jul 19
Re: [dadi-user] Seeking Help with Model Selection Instability in dadi
Hello Fred, Sorry for the slow reply. I've been on vacation. I'm not deeply familiar with the
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Re: [dadi-user] Seeking Help with Model Selection Instability in dadi
Hello Fred, Sorry for the slow reply. I've been on vacation. I'm not deeply familiar with the
Jul 19
Sofia Hayden Bofill
,
Ryan Gutenkunst
3
Jul 7
Converting migration fraction to number of migrants
Hi Ryan, Thank you so much for your quick reply, I really appreciate it. Amazing, now it is clear.
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Converting migration fraction to number of migrants
Hi Ryan, Thank you so much for your quick reply, I really appreciate it. Amazing, now it is clear.
Jul 7
dadi-user
Jul 6
Seeking Help with Model Selection Instability in dadi
Hi, I am writing to seek your expertise regarding an issue I've encountered while using dadi for
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Seeking Help with Model Selection Instability in dadi
Hi, I am writing to seek your expertise regarding an issue I've encountered while using dadi for
Jul 6
Sarah Babaei
,
Ryan Gutenkunst
4
Jul 1
2D sfs and results interpretation
Hi Sarah, Replies below On Jul 1, 2025, at 11:20 AM, Sarah Babaei <sarahba...@gmail.com>
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2D sfs and results interpretation
Hi Sarah, Replies below On Jul 1, 2025, at 11:20 AM, Sarah Babaei <sarahba...@gmail.com>
Jul 1
Panos Zerv
,
Ryan Gutenkunst
2
May 19
dadi-cli optimization method
Hello Panagiotis, There is not currently a way to specify the optimization method in dadi-cli. If you
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dadi-cli optimization method
Hello Panagiotis, There is not currently a way to specify the optimization method in dadi-cli. If you
May 19
Linda H
,
Ryan Gutenkunst
5
Apr 8
low theta, strange parameter values
Hi Ryan, Thanks for clarifying down-projection, it really doesn't seem to be useful in this case.
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low theta, strange parameter values
Hi Ryan, Thanks for clarifying down-projection, it really doesn't seem to be useful in this case.
Apr 8
Hugo D
,
Ryan Gutenkunst
2
Apr 1
Bias in residuals after physical pruning
Hello Hugo, This is a bit perplexing. If you have a well-fitting model with the unprojected data, I
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Bias in residuals after physical pruning
Hello Hugo, This is a bit perplexing. If you have a well-fitting model with the unprojected data, I
Apr 1
HC Lim
,
Ryan Gutenkunst
9
Mar 29
Any implementation of population fusion models?
Hi Ryan, That's correct - giving it a 2D sfs solved the problem (but run didn't converge but
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Any implementation of population fusion models?
Hi Ryan, That's correct - giving it a 2D sfs solved the problem (but run didn't converge but
Mar 29
Hugo D
,
Ryan Gutenkunst
3
Mar 26
Unrealistic parameters conversion
Hi Ryan, Thank you for confirming that there isn't an issue with the computation procedure. You
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Unrealistic parameters conversion
Hi Ryan, Thank you for confirming that there isn't an issue with the computation procedure. You
Mar 26
Maria Paula Rodriguez
,
Ryan Gutenkunst
5
Mar 18
nonparametric bootstrap files contain only zeros
Hi Ryan It worked!! Thank you very much. Maria El mar, 18 mar 2025 a las 13:43, Ryan Gutenkunst (<
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nonparametric bootstrap files contain only zeros
Hi Ryan It worked!! Thank you very much. Maria El mar, 18 mar 2025 a las 13:43, Ryan Gutenkunst (<
Mar 18
Mathilde SALAMON
,
Ryan Gutenkunst
6
Jan 15
Confirming results 1D model growth vs two-epochs vs bottlegrowth
Hello Mathilde, Sorry for the slow reply. I don't know about the complex generation structure;
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Confirming results 1D model growth vs two-epochs vs bottlegrowth
Hello Mathilde, Sorry for the slow reply. I don't know about the complex generation structure;
Jan 15
Lena Zemlemerova
,
Ryan Gutenkunst
2
12/16/24
problems with optimization and convergence
Hello Lena, Sorry for the slow reply. I'm not super familiar with the Portik pipeline, so
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problems with optimization and convergence
Hello Lena, Sorry for the slow reply. I'm not super familiar with the Portik pipeline, so
12/16/24
Morgan L. Lynn
,
Ryan Gutenkunst
2
10/29/24
Folded Spectrum in python is not recognizing some of the individuals in my VCF file
Hello Morgan, This may occur if you often have missing data. For a site to enter the spectrum for 10
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Folded Spectrum in python is not recognizing some of the individuals in my VCF file
Hello Morgan, This may occur if you often have missing data. For a site to enter the spectrum for 10
10/29/24
Alexandra Sumarli
,
Ryan Gutenkunst
2
10/15/24
dadi-cli GenerateFS issue
Hello Alexandra, It's not obvious to me where this issue could be arising. Can you send a subset
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dadi-cli GenerateFS issue
Hello Alexandra, It's not obvious to me where this issue could be arising. Can you send a subset
10/15/24
钱晓波
,
Ryan Gutenkunst
7
10/14/24
Confused with effective sequenced length (L)
Hello Xiaobo, Once the data are parsed, it doesn't matter how many SNPs you have. So I would not
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Confused with effective sequenced length (L)
Hello Xiaobo, Once the data are parsed, it doesn't matter how many SNPs you have. So I would not
10/14/24
Skye Davis
, …
Ryan Gutenkunst
13
9/27/24
dadi-cli 3D model plotting issue
Hello Skye, You got the right email address. My apologies for not responding sooner; it fell of my
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dadi-cli 3D model plotting issue
Hello Skye, You got the right email address. My apologies for not responding sooner; it fell of my
9/27/24
Patrick McKenzie
,
Ryan Gutenkunst
2
9/11/24
GIM_uncert computational time
Hello Patrick, Sorry for the slow reply! I'm not sure what could be going with your analysis. The
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GIM_uncert computational time
Hello Patrick, Sorry for the slow reply! I'm not sure what could be going with your analysis. The
9/11/24
Yuanshu Pu
,
Ryan Gutenkunst
2
8/29/24
global optimum, parameter estimation variations, and nested models comparison
Hello Yuanshu, See responses below. On Aug 22, 2024, at 9:18 AM, Yuanshu Pu <yuans...@evobio.eu
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global optimum, parameter estimation variations, and nested models comparison
Hello Yuanshu, See responses below. On Aug 22, 2024, at 9:18 AM, Yuanshu Pu <yuans...@evobio.eu
8/29/24
chichi zhao
, …
Ryan Gutenkunst
4
8/28/24
Make_plots.py problems
Hello Niloo, It looks like you're using some sort of external pipeline to drive dadi, so I can
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Make_plots.py problems
Hello Niloo, It looks like you're using some sort of external pipeline to drive dadi, so I can
8/28/24
Gutenkunst, Ryan N - (rgutenk)
8/7/24
Genomic History Inference Strategies Tournament
Hello dadi users, The 2024 Genomic History Inference Strategies Tournament (GHIST) is live! If you
unread,
Genomic History Inference Strategies Tournament
Hello dadi users, The 2024 Genomic History Inference Strategies Tournament (GHIST) is live! If you
8/7/24
Alejandro Calderon
,
Ryan Gutenkunst
2
8/5/24
dadi and dadi-cli import error
Hello Alejandro, This is caused by a recent change in scipy. The latest version of dadi on Bitbucket
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dadi and dadi-cli import error
Hello Alejandro, This is caused by a recent change in scipy. The latest version of dadi on Bitbucket
8/5/24
Alexandra Sumarli
,
Ryan Gutenkunst
2
7/5/24
dadi-cli: import model syntax error
Hello Alex, I think the issue is the use of (n1,n2) in the arguments list. It should be easy to fix.
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dadi-cli: import model syntax error
Hello Alex, I think the issue is the use of (n1,n2) in the arguments list. It should be easy to fix.
7/5/24
Lorenzo Bertola
, …
Ryan Gutenkunst
6
6/7/24
1D SFS from ANGSD with lcWGS data vs 1D SFS from easySFS with ddRAD data
Hello Ryan, Thank you very much for your input! That would make a lot of sense, as the U shape is
unread,
1D SFS from ANGSD with lcWGS data vs 1D SFS from easySFS with ddRAD data
Hello Ryan, Thank you very much for your input! That would make a lot of sense, as the U shape is
6/7/24
Katharine Prata
,
Ryan Gutenkunst
4
6/7/24
Strong patterning in residuals: model choice or unrealistic spectra?
Hello Kat, The biggest outlier I see is the large excess of SNPs in the data versus model that are
unread,
Strong patterning in residuals: model choice or unrealistic spectra?
Hello Kat, The biggest outlier I see is the large excess of SNPs in the data versus model that are
6/7/24
Katharine Prata
,
Ryan Gutenkunst
4
6/3/24
Apparent excess of mid-frequency alleles in 1d-spectrum
Hi, I thought I'd update everyone in the group about how we (hopefully) resolved this issue. We
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Apparent excess of mid-frequency alleles in 1d-spectrum
Hi, I thought I'd update everyone in the group about how we (hopefully) resolved this issue. We
6/3/24
Gutenkunst, Ryan N - (rgutenk)
5/19/24
donni (demographic inference from spectra using ML) paper published
Hello dadi users, The paper describing donni, our new machine-learning approach to demographic
unread,
donni (demographic inference from spectra using ML) paper published
Hello dadi users, The paper describing donni, our new machine-learning approach to demographic
5/19/24