Jactivemodules and PPI network without numerical expression data

[pedr...@gmail.com]

Hello,
I am currently analysing a PPI network built around upregulated proteins from a shotgun experiment. I was wondering if I could use jactivemodules to extract subnetworks based on topological criteria, even if I do not have a p value or other numerical values related to the expression of the proteins.
Thanks

[Scooter Morris]

Hi Pedro,
   I think you probably want something like MCODE (see the MCODE app or clusterMaker2).

-- scooter

[falsafi...@gmail.com]

در پنجشنبه 6 ژوئیهٔ 2017، ساعت 20:38:28 (UTC+4:30)، Scooter Morris نوشته:

Hi scooter,

I have a similar question, but I want to extract active or differential modules, and as you know, MCODE don't take it. could you please guide me?