Hi Rakesh,
There are a number of Apps that provide a front-end via a Cytoscape App that communicates with a web service.
Our Diffusion app is one of these, and you can see how it was implemented as an App
here, as well as a service
here.
This is just one of many ways to achieve this; the specific details of the implementation will be up to you.
Is this what you had in mind?
David Otasek