Cumulus 4.0.3 is released

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Yiming Yang

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Apr 6, 2026, 8:59:08 PMApr 6
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Hello All,

Cumulus version 4.0.3 is released.

The release notes can be viewed at https://github.com/lilab-bcb/cumulus/releases/tag/4.0.3.

The workflows are published on Dockstore at https://dockstore.org/organizations/lilab/collections/Cumulus.

The user guide documentation is at https://cumulus.readthedocs.io/en/4.0.3/.

## 4.0.3 (2026-04-06)

### Cellranger workflow:

* Fix a bug in processing 10x On-Chip Multiplexing (OCM) data.
* Support input FASTQ files in unzipped ".fastq" format.

### Demultiplexing workflow:

* For Souporcell, add "souporcell_umi_tag" to allow users specify a custom UMI tag other than the default "UB" for their data.


Sincerely,
Yiming
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