FUSION weights data

[Nina Yifan Yang]

Hi Team,

I tried to add FUSION weights data in my analysis, ~17000 in total. I also added whole genome LD matrices in as well. It stopped in the middle of process, and reported an error message “RAM reached the maximum”. I have 18GB RAM on my computer. Anyone could help?

Thanks,

[Kevin Luo]

Hello,

The LD matrices are very large, and loading them in memory could crash the memory. Please only provide the paths to the LD matrices in the LD_map and region_metatable. We highly recommend running ctwas on HPC clusters with large memory (50GB RAM or more). If you have memory problems, you should use a lower number of ncore, or even ncore = 1.  

Hope this helps,

Kevin

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