Cecil Textbook

[Arlyne Doepner]

Itwas first published in 1927 as the Textbook of Medicine, by Russell LaFayette Cecil.[2][3] In the United States, it is a prominent and widely consulted medical textbook.[3] Cecil Medicine is often compared with Harrison's Principles of Internal Medicine, which it predates by three decades.[3] Approximately one third of its authors are changed with each new edition.[4]

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Background: Cholera is a potentially lethal diarrheal disease produced by Vibrio cholerae serotypes O1 El Tor and O139. Known since antiquity, the condition causes epidemics in many areas, particularly in Asia, Africa, and South America. Left untreated, the mortality may reach 50%. The crucial therapeutic intervention is intravenous or oral rehydration and correction of acidosis, dyselectrolytemia, and renal impairment. Antibiotic use represents the main pharmacological intervention.

Study design: To determine the changes in the experts' approach to the management of cholera and particularly the use of antibiotics as presented in a widely used textbook in the United States.

Results: Sulfonamides were recommended in 1947, followed by the introduction of tetracyclines, chloramphenicol, and furazolidone in 1955. The options were restricted in 2000 to doxycycline. In the past decade, patients infected with strains known to have a degree a resistance to tetracyclines were treated with azithromycin or ciprofloxacin. Antibiotic use decreases the volume of stool and the duration of diarrhea but has not been considered lifesaving. Drugs with antimotility, antiemetic, or antisecretory properties are not useful.

The Cecil Medicine is a hefty book (>3000 pages) and previous posts seem to recommend a Cecil book for the IM rotation. I'm just not sure which (i.e. the "Essentials" or the full length one) is recommended?

I prefered the Essentials Version. The text is much clearer, there are some nice colorful pictures and diagrams and there's definitely not a paucity of information. For a more detailed (though less well explained) textbook for Medicine, especially if you're planning on Internal Medicine, I would go for the Harrison's complete version rather than the Cecil's, but the Cecil's Essentials is definitely a nice one to have for clerkship (and residency).

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