An updated version of the CPR.owl document was committed into the
subversion repository with the following additions (for which feedback
is welcome):
http://code.google.com/p/cpr-ontology/source/browse/trunk/CPR.owl
- the hasMethod relationship asserted on instances of therapeutic
procedures not has as its domain cpr:SurgicalMethod instead of just
Method
- cpr:SurgicalMethod is a subclass of biotop:Affecting - in similar
fashion to GALEN's SurgicalDeed which are characterized by
SurgicalProcedures and/or SNOMED-CT's surgical methods (Dissecting,
Removal, etc..)
- cpr:organismal-process replaced with biotop:BiologicalProcessualEntity
- cpr:clinical-act is now a subclass of biotop:ProcessualEntity rather
than biotop:Action (it is more general than BioTop's notion of an
action)
- cpr:etiological-agents now only are the cause of
pathological-dispositions (per C. Whitbecks account of disease
etiology)
- cpr:genetic-disorder replaced with cpr:genetic-abnormality and
defined as a cpr:etiologic-agent ro:located_in SOME biotop:NucleicAcid
- removal of abnormal-homeostasis
- addition of PhysiologicalOrAnatomicalAlteration a subclass of
biotop:Affecting that necessarily ro:has_participant SOME
cpr:physical-anatomical-entity - this corresponds to C. Whitbecks
account of diseases as necessarily involving sequences of pathological
changes to anatomical structures or function at the level of cells and
tissues
- pathological-disposition definition changed to reflect i) that they
are realized as pathological-processes (and not necessarily symptoms)
ii) they are the consequence of an etiological-agent or a biological
process in which the etiological-agent is a participant iii) that they
are also realized as PhysiologicalOrAnatomicalAlterations
- sign is now a primitive (since there are as yet no putative
sufficient conditions) despite the fact that they are typically not
considered universals
- symptoms are a defined class (since they seem to have agreeable
sufficient conditions): the perception of a bodily feature by the
patient and hypothesized by them to be the realization of a
pathological-disposition (since OWL is not an epistemological logic,
the belief of the patient cannot be captured)
-- Chime