August2023 update: osu! Wineskins for macOS, osu!macOS Agent, and this osu!mac documentation website is no longer officially supported or maintained. Official support will no longer be provided by the authors of these respective projects on the osu! forums. You can read more information about this change from Technocoder and aidswidjaja. Thank you for everything.
Currently, we are experiencing a considerable number of issues in relation to getting osu! to work, including issues with the .NET framework. The exit code in a standard run indicates a low-level garbage collection issue, while running osu!.exe through Wine Command Prompt will return a binary translation error. However, we are still not entirely sure what is causing this issue and/or how to rectify it. You can try some of the Resolution steps below; success may vary.
On the bleeding edge? Once you update to dotnet452, you will not be able to immediately revert to an older version. You may need to completely uninstall dotnet452 and then install an older version of dotnet, for which instructions are not provided here.
3a8082e126