[Announcement] New Calcium Imaging Analysis Framework: OptiNiSt

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Yukako Yamane

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Jun 27, 2025, 3:15:02 PMJun 27
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Dear Colleagues,

We are pleased to announce the publication of a paper describing
OptiNiSt (Optical Neuroimage Studio), a new open-source framework for
calcium imaging data analysis. OptiNiSt was developed as part of the
AMED(Japan Agency for Medical Research and Development) Brain/MINDS
project.

Article: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1013087

OptiNiSt is a flexible and reproducible pipeline construction tool
that supports calcium imaging data analysis. Featuring an intuitive
graphical user interface, it facilitates data sharing and
standardization of analysis workflows across research groups.

GitHub (source code): https://github.com/oist/optinist
Documentation & Tutorials: https://optinist.readthedocs.io/en/latest/

We hope OptiNiSt will be a helpful tool for your research. Feedback
and questions are always welcome.

Best regards,
Yukako Yamane  & Kenji Doya
Neural Computation Unit
Okinawa Institute of Science and Technology (OIST)

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