RE: information on Corra
Mi-Youn Brusniak
Thank you for being interested in Corra!
Corra is heavily used in several institutions for high MS1 accuracy machines
like Orbi and FT dataset. I am not quite familiar with MALDI TOF TOF and
don't know how well Corra will do with MALDI data. More specifically, You
can use
http://tools.proteomecenter.org/wiki/index.php?title=Software:ReAdW to
convert ABI raw file to mzXML and try out Corra.
Let me know how things are turned out!
Cheers,
Mi-Youn.
Mi-Youn Brusniak, Ph.D.
Computational Biology
Seattle Proteome Center
mbru...@systemsbiology.org
Tel: (206) 732-1327
-----Original Message-----
From: Silvia Rocchiccioli [mailto:silvia.ro...@ifc.cnr.it]
Sent: Thursday, October 15, 2009 3:28 AM
To: mbru...@systemsbiology.org
Subject: information on Corra
Hello Mi-Youn,
I am a Post-Doc student at the Institute of Clinical Physiology in Pisa
(Italy). We work on plasma proteomics for biomarker discovery in
cardiovascular disease.
We use mass spectrometry (LC-MALDI application) for identification and
comparative analysis of peptide profiles. Our approach is a label-free
LC-MS-based quantitative proteomic methodology. I discovered your
software Corra and It seems very useful also for statistical analysis.
We have a 4800 MALDI TOF TOF Analyzer (Applied Biosystem) and we adopt
an HPLC separation before maldi analysis. So at the end for every sample
we can create a profile (rt- m/z- intensity) using a tool named mzML
Exporter (Applied Biosystem/SCIEX).
Is mzML format supported by your software?
If not, could you suggest me any tools for conversion from mzML to mzXML?
Thank you in advance
Best Regards
Silvia
--
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Silvia Rocchiccioli, PhD
Istituto di Fisiologia Clinica-CNR
Via Moruzzi 1
56124, Pisa
Tel: 050 315 3312
email:silvia.ro...@ifc.cnr.it
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