BUY 5F-AKB48 POWDER

[Research Chem updates]

BUY 5F-AKB48 POWDER (also known as 5F-AKB-48 or 5F-APINACA) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as despite not being disclosed as an example, it is very similar to the corresponding pentanenitrile and 4-chlorobutyl compounds which are claimed as examples 3 and 4. In the United States, 5F-AKB48 is a Schedule I controlled substance.

5F-AKB48 is an Anlage II controlled drug in Germany since July 2013. As of October 2015, 5F-AKB48 is a controlled substance in China.

5F-AKB48 is banned in the Czech Republic.

5F-AKB48 was first identified in South Korea. It is expected to be a potent agonist of the CB1 receptor and CB2 receptor. Its metabolism has been described in literature.

Chemical and physical data
Formula: C23H30FN3O

Molar mass: 383.5 g/mol g·mol?1

Pharmacology
5F-AKB48 acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.

See also
5F-ADB
5F-AMB
AB-FUBINACA
AB-CHFUPYCA
AB-PINACA
ADB-CHMINACA
ADB-FUBINACA
ADB-PINACA
ADBICA
APICA
APINACA
FUB-APINACA
MDMB-CHMICA

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Buy 3-fpm ( 3-Fluorophenmetrazine ), Buy 3-fpm crystalline powder
Buy 3-fpm crystalline powder (also known as 3-FPM, 3-FPH and PAL-593) is a phenylmorpholine-based stimulant and fluorinated analogue of phenmetrazine that has been sold online as a designer drug.

Stereoisomers
3-FPM is a derivative of phenmetrazine. As described by McLaughlin and colleagues
(7), “the fluorinated analogs of phenmetrazine contain two chiral centers which yield the potential for four stereoisomers and two racemic mixtures (i.e., cis- and trans-racemates)

Physical appearance
3-Fluorophenmetrazine is a white, solid, crystalline powder. It was also identified in
yellow, blue or green pellets (tablets).

Chemical name
IUPAC name: 2-(3-fluorophenyl)-3-methylmorpholine; hydrochloride.

Identification and analysis
A number of analytical tests have been used to differentiate 3-FPM from its positional isomers, 2- and 4-FPM, including gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, and thin-layer chromatography (7). All of the methods successfully differentiated 3-FPM from its.

Pharmacodynamics
3-FPM is potent at releasing dopamine (DA) and norepinephrine (NE), with half
maximal effective concentration (EC50) values of 43 and 30 nM, respectively, and
less potent at releasing serotonin (5-HT; 2558 nM (1)).

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