Hello
Hossam,
in general, you can write ODE's for compartments, species or global quantities. For general ODE's that don;t fit the scheme, where species (which reside in compartments) and partake in reactions / processes, I would suggest to write the ODE on a global quantity. And for clarification if the simulation type of a species is reaction, that means it will be produced or consumed, as given by the stoichiometry and speed of the reaction it partakes in. In that case you would not be able to enter an ODE at all.
That being said, your equation does require to differentiate with respect to space as well as time. This is not the kind of equation supported by COPASI.
best
Frank