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Andrew Weller
12/23/25
Multiple concentration starting points
Hi all. What I hope will be a straightforward question for the experts. I am fitting multiple
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Multiple concentration starting points
Hi all. What I hope will be a straightforward question for the experts. I am fitting multiple
12/23/25
Camilo Mejia P.
,
Sahle, Dr. Sven
3
12/20/25
Chemistry student help
Thank you very much, Sven. I have a few more questions. When the parametric estimation finishes
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Chemistry student help
Thank you very much, Sven. I have a few more questions. When the parametric estimation finishes
12/20/25
Gia Shelp
,
Hoops, Stefan (sh9cq)
3
11/27/25
Reaction with multiple substrates and products
Hi Stefan, Thank you for your quick reply. I double checked, and yes, all my concentrations and
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Reaction with multiple substrates and products
Hi Stefan, Thank you for your quick reply. I double checked, and yes, all my concentrations and
11/27/25
Riccardo Amorati
,
Pedro Mendes
2
10/17/25
Simulation of Radical Chains in Multiple Small Droplets Using Stochastic Method
Hi Riccardo, From your description I think you have two alternative ways out: 1 - using parameter
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Simulation of Radical Chains in Multiple Small Droplets Using Stochastic Method
Hi Riccardo, From your description I think you have two alternative ways out: 1 - using parameter
10/17/25
Sara Biamonte
,
Matthias König
5
10/13/25
Struggling with COPASI plots – student seeking guidance
Hi Matthias, Thank you very much for taking the time to reproduce the simulations and for your
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Struggling with COPASI plots – student seeking guidance
Hi Matthias, Thank you very much for taking the time to reproduce the simulations and for your
10/13/25
Marc Lefranc
,
Frank Bergmann
5
10/13/25
Problems with copasi on Debian 13 "Trixie"
Do you think it would be possible for you to send me the script / model privately? I'd be happy
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Problems with copasi on Debian 13 "Trixie"
Do you think it would be possible for you to send me the script / model privately? I'd be happy
10/13/25
Melanie Stefan
, …
Matthias König
5
10/13/25
Installing Copasi on Manjaro Linux: Problem and Solution
I am having the same issues with Linux mk-op1 6.14.0-33-generic #33~24.04.1-Ubuntu SMP
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Installing Copasi on Manjaro Linux: Problem and Solution
I am having the same issues with Linux mk-op1 6.14.0-33-generic #33~24.04.1-Ubuntu SMP
10/13/25
Nausheen Fatima
,
Frank Bergmann
5
9/30/25
flux plots
Thank you. Did you see the flux plots as well? They are not changing for me even when I change the
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flux plots
Thank you. Did you see the flux plots as well? They are not changing for me even when I change the
9/30/25
Jordi Solà
,
Pedro Mendes
2
9/16/25
Total concentration in reversible reaction
Hi there, welcome yes, you can create a new variable in COPASI that is the sum of the two species S
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Total concentration in reversible reaction
Hi there, welcome yes, you can create a new variable in COPASI that is the sum of the two species S
9/16/25
Frank Bergmann
2
9/12/25
Workshop Announcement: Advanced Modelling with COPASI (In-person Workshop Oct, 10th, in Heidelberg, Germany)
Please register for our workshop parameter estimation techniques using COPASI, a leading software
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Workshop Announcement: Advanced Modelling with COPASI (In-person Workshop Oct, 10th, in Heidelberg, Germany)
Please register for our workshop parameter estimation techniques using COPASI, a leading software
9/12/25
artur....@posteo.de
, …
juergen
19
8/5/25
Reaction Event Fluxes
Dear All, Just a few further comments to this discussion: Reaction extents can still not be selected
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Reaction Event Fluxes
Dear All, Just a few further comments to this discussion: Reaction extents can still not be selected
8/5/25
Daniel Arismendi
, …
Sahle, Dr. Sven
5
8/4/25
Help Needed: Discrepancy in Simulation of Equivalent Kinetic Equations
Dear all, I managed to handle the different cases using conditional statements (see attached cps file
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Help Needed: Discrepancy in Simulation of Equivalent Kinetic Equations
Dear all, I managed to handle the different cases using conditional statements (see attached cps file
8/4/25
Dante Kienigiel
,
juergen
2
8/4/25
Record when reactions happen
Please see discussion at: groups.google.com/g/copasi-user-forum/c/U2qYtRqSd-A/m/YL7sZcJWAwAJ
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Record when reactions happen
Please see discussion at: groups.google.com/g/copasi-user-forum/c/U2qYtRqSd-A/m/YL7sZcJWAwAJ
8/4/25
Evangelos Koutsouadis
, …
juergen
6
8/4/25
Exact Simulation Steps in Stochastic Simulation
Dear All, Just a few further comments to this discussion: Reaction extents can still not be selected
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Exact Simulation Steps in Stochastic Simulation
Dear All, Just a few further comments to this discussion: Reaction extents can still not be selected
8/4/25
Nausheen Fatima
,
Frank Bergmann
6
7/11/25
inhibition reaction
Hello Nausheen, the image shows the difference of the manual edits. Where instead of a generic
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inhibition reaction
Hello Nausheen, the image shows the difference of the manual edits. Where instead of a generic
7/11/25
Stephan MG
7/9/25
Measure execution time of model simulation
Dear all, we are currently working with COPASI and imported SBML models for which we do time course
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Measure execution time of model simulation
Dear all, we are currently working with COPASI and imported SBML models for which we do time course
7/9/25
Marc Lefranc
, …
Stephan MG
15
7/8/25
Compiling C++ programs using the copasi library
Hi Frank, thanks again. I think this is the the cleanest approach. No rush to create a template or
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Compiling C++ programs using the copasi library
Hi Frank, thanks again. I think this is the the cleanest approach. No rush to create a template or
7/8/25
Nausheen Fatima
,
Frank Bergmann
3
7/2/25
inhibition reaction
Thanks Frank! I have an inhibition for a receptor and it will be competitive inhibition with another
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inhibition reaction
Thanks Frank! I have an inhibition for a receptor and it will be competitive inhibition with another
7/2/25
Ahmed Atta
, …
Matthias König
4
5/7/25
How to Handle Species with Mixed Units in COPASI and Why It Divides by Compartment Volume
Converting species from concentrations to amounts is complex and highly dependent on the structure of
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How to Handle Species with Mixed Units in COPASI and Why It Divides by Compartment Volume
Converting species from concentrations to amounts is complex and highly dependent on the structure of
5/7/25
Marc Lefranc
,
Pedro Mendes
2
5/2/25
Sensitivity analysis
Hi Marc, Yes, the sensitivity analysis tool, when applied to time course, only takes into
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Sensitivity analysis
Hi Marc, Yes, the sensitivity analysis tool, when applied to time course, only takes into
5/2/25
Sebastián
, …
Hoops, Stefan (sh9cq)
3
5/1/25
Zero-order reaction (Gillespie/stochastic simulation)
Hello Sebastian, Zero order (constant) reaction kinetics can be used in COPASI with stochastic
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Zero-order reaction (Gillespie/stochastic simulation)
Hello Sebastian, Zero order (constant) reaction kinetics can be used in COPASI with stochastic
5/1/25
Marc Lefranc
,
Frank Bergmann
2
4/8/25
Compute time course until an event is triggered
Hello Marc, You could try the following: - create an additional event assignment for your event, that
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Compute time course until an event is triggered
Hello Marc, You could try the following: - create an additional event assignment for your event, that
4/8/25
Harry Wilson
,
Pedro Mendes
3
3/18/25
Insights on rate constants obtained via parameter estimation
*** Attention: This is an external email. Use caution responding, opening attachments or clicking on
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Insights on rate constants obtained via parameter estimation
*** Attention: This is an external email. Use caution responding, opening attachments or clicking on
3/18/25
sanjana kb
, …
Matthias König
4
3/14/25
How to implement summation term with upper and lower limits in COPASI
Hi Sanjana, I have a similar use case, and I use sbmlutils to create models programmatically in
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How to implement summation term with upper and lower limits in COPASI
Hi Sanjana, I have a similar use case, and I use sbmlutils to create models programmatically in
3/14/25
Harry Wilson
, …
Pedro Mendes
16
3/5/25
Automation of Copasi
*** Attention: This is an external email. Use caution responding, opening attachments or clicking on
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Automation of Copasi
*** Attention: This is an external email. Use caution responding, opening attachments or clicking on
3/5/25
Stephane Ransac
, …
Hoops, Stefan (sh9cq)
9
3/1/25
multicore processing ?
Hello Pedro, I found a Linux server on which I can run CopasiSE. So I should be able to test the
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multicore processing ?
Hello Pedro, I found a Linux server on which I can run CopasiSE. So I should be able to test the
3/1/25
Foster Carr
2/27/25
Looking for COPASI Software experts for contracted work.
Hi Everyone, My company is looking for a COPASI expert to build a model of a multiplex (2 analytes)
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Looking for COPASI Software experts for contracted work.
Hi Everyone, My company is looking for a COPASI expert to build a model of a multiplex (2 analytes)
2/27/25
Blinov,Michael
2/14/25
Attention Modeling Community
*** Attention: This is an external email. Use caution responding, opening attachments or clicking on
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Attention Modeling Community
*** Attention: This is an external email. Use caution responding, opening attachments or clicking on
2/14/25
Nausheen Fatima
2/11/25
receptor recycling
Hi, I am building a model that involves a reaction of a receptor binding with the ligand and then
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receptor recycling
Hi, I am building a model that involves a reaction of a receptor binding with the ligand and then
2/11/25
Harry Wilson
,
Frank Bergmann
5
2/5/25
Multiple concentration
Dear Frank, That helped me a lot to run the experiment in copasi. Like I said, the initial
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Multiple concentration
Dear Frank, That helped me a lot to run the experiment in copasi. Like I said, the initial
2/5/25