For a couple of years, the files in Computer 1 were in the Mac user folder (Documents, Downloads, and Desktop), not the Dropbox folder. I used Dropbox Backup to keep these backed up. These made a copy in a special folder in Dropbox > Mac.
The Dropbox > Mac folder was easily accessible from Computer 2 and Computer 3. Whenever I worked on those computers, I worked entirely within this folder, keeping everything nicely in sync among all three computers, and everything was easily accessible via the Mac Finder like any other file.
Now, due to a recent change to Dropbox Backup, the Dropbox Backup from Computer 1 is only accessible via the web interface. It is no longer accessible in my Finder in Computer 2 or Computer 3. Those files, which were previously available on my local drive, seem to have been totally deleted.
Moreover, if I attempt to "Restore" the backup from Computer 1 onto Computer 2, Dropbox prompts me to create a new backup of Computer 2. I don't need this, but I was forced to accept it in order to proceed with the Restore. Then, after accepting the new backup, I cannot restore from Computer 1.
At the moment, the only was of accessing my important files is via the web, and the only local copy is on Computer 1, which is in a different location. Please help me restore this to the old system, where I can have three computers always in sync.
Did this post not resolve your issue? If so please give us some more information so we can try and help - please remember we cannot see over your shoulder so be as descriptive as possible!
Better don't rely anymore on extravagant features like Dropbox Backup. While you need sync only, backup is not intended for such a usage! Just create a simple folder in your Dropbox folder named Documents and put everything you need to keep in sync there. Turn off your Dropbox Backup (on every machine it has been on) and just... sync without backup. You will have one more Documents folder - use the one that's in Dropbox folder that you created. That's it.
Thanks. Yes, I have realized that this is the most likely way forward. For now, I am trying to use Rewind to rewind the contents of the previous Backup folder, which is still showing in the Dropbox but now as a regular Dropbox folder. So far it seems promising, but it will probably take some time to rewind 175 GB. I will report back further. Then it will be just another Dropbox folder, as you suggest.
Dropbox Rewind has concluded, and appears to be a satisfactory solution in this circumstance. I do think there should be a better migration for customers in this scenario, but I hope my experience will help others.
I had a honeymoon period of between 6 months and a year with Dropbox when it pretty much kept synching from my Macbook pro --- then, it was rocky, undependable, then it just quit synching. Any advice here from a Dropbox rep did not help at all. I am switching to using a PC from Mac this week, and hoping I will have a better outcome on Dropbox.
When exploring datasets of published papers, more often that what I'd like I realize that the genes present in the dataset, and the annotation file version mentioned in the materials & methods do not match.
Usually I end up with a list of genes present in the data but that do not exist in the annotation version that was supposedly used. Then it is my turn to enter into a spiral of testing different ensembl/gencode versions until I find the version that misses the least genes (spoiler: there is never a perfect match).
Edit: I've found this tool to search for synonymous gene names -symbol-checker/ which is another common problem in this.However, it doesn't tell you when did the name change happen, so you cannot start digging for annotation versions older than that.
However, I fail to see which one of these courses can help me identify which version of the annotation files contains a deprecated gene symbol or alias. Or which source was really used and then misreported in the material and methods of the article. Could you guide me through the linked courses which one can help me with this kind of issue?
However, using gencode v35, now there are 46 genes form the dataset not matching the annotation. Some of them are those with old aliases. But now there are 15 genes that have been removed from gencode since version v33 (their gene_id has been removed from ensembl its last appearance was v100)
based on your answer, it seems like you are doing this yourself. this is how most people start, but generally speaking it is a better use of time to draw on other resources that have already done this.
anyway, once you have what you consider to be a plausible superset of possible annotation Dbs, simply run all against all. the smoking gun is if one annotation Db actually gets all of them; but if this doesnt happen you have recourse...
Hi,I had the exact same problem and made a tool. It doesn't supply when the change happened like you specify but does show which gene symbol (approved, alias or previos) in which reference annotation. Output is text and important part is the warnings parts at the header. I have been the only user so I am curious if it is any use to anyone else. :)
This tool maps aliases, and previous or withdrawn symbols to current approved HGNC symbols as well as check for any entries thatare not gene symbols and fix capitalizations. Ensembl and RefSeqannotation files sometimes use previous or alias symbols. This toolalso cross checks against Ensembl and NCBI annotation files fordifferent genome versions and shows which gene symbols used. This wayan accurate gene set can be utilized to avoid false negatives in thevariant discovery process. The source code is available on GitHub.
i will try the tool out - one thought (pre testing) is that this would possibly be better pitched as a bioconductor package or even an adjunct to an existing effort (rather than in the shell). thoughts?
Explore the most recent data on the drug situation in Europe provided by the EU Member States. These datasets underpin the analysis presented in the agency's work. Most data may be viewed interactively on screen and downloaded in Excel format.
We have developed a systemic approach that brings together the human networks, processes and scientific tools necessary for collecting, analysing and reporting on the many aspects of the European drugs phenomenon.
This is the final version of the questionnaire on drug use among prisoners at European level. The questionnaire is the results of several years of work in the field of drugs and prison, which has included the agreement on a methodological framework or monitoring drug and prison in Europe, the analysis of existing questionnaires and a discussion among high level experts from several European countries and international organizations.
Note: The following text is a transcription of the Stone Engraving of the parchment Declaration of Independence (the document on display in the Rotunda at the National Archives Museum.) The spelling and punctuation reflects the original.
The unanimous Declaration of the thirteen united States of America, When in the Course of human events, it becomes necessary for one people to dissolve the political bands which have connected them with another, and to assume among the powers of the earth, the separate and equal station to which the Laws of Nature and of Nature's God entitle them, a decent respect to the opinions of mankind requires that they should declare the causes which impel them to the separation.
We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty and the pursuit of Happiness.--That to secure these rights, Governments are instituted among Men, deriving their just powers from the consent of the governed, --That whenever any Form of Government becomes destructive of these ends, it is the Right of the People to alter or to abolish it, and to institute new Government, laying its foundation on such principles and organizing its powers in such form, as to them shall seem most likely to effect their Safety and Happiness. Prudence, indeed, will dictate that Governments long established should not be changed for light and transient causes; and accordingly all experience hath shewn, that mankind are more disposed to suffer, while evils are sufferable, than to right themselves by abolishing the forms to which they are accustomed. But when a long train of abuses and usurpations, pursuing invariably the same Object evinces a design to reduce them under absolute Despotism, it is their right, it is their duty, to throw off such Government, and to provide new Guards for their future security.--Such has been the patient sufferance of these Colonies; and such is now the necessity which constrains them to alter their former Systems of Government. The history of the present King of Great Britain is a history of repeated injuries and usurpations, all having in direct object the establishment of an absolute Tyranny over these States. To prove this, let Facts be submitted to a candid world.
He has forbidden his Governors to pass Laws of immediate and pressing importance, unless suspended in their operation till his Assent should be obtained; and when so suspended, he has utterly neglected to attend to them.
He has refused to pass other Laws for the accommodation of large districts of people, unless those people would relinquish the right of Representation in the Legislature, a right inestimable to them and formidable to tyrants only.
He has called together legislative bodies at places unusual, uncomfortable, and distant from the depository of their public Records, for the sole purpose of fatiguing them into compliance with his measures.
He has refused for a long time, after such dissolutions, to cause others to be elected; whereby the Legislative powers, incapable of Annihilation, have returned to the People at large for their exercise; the State remaining in the mean time exposed to all the dangers of invasion from without, and convulsions within.
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