I used to think iTP was based on Apache, but was corrected a few years
back by somoen in the know. Configuration is similar to apache but
many Apache 'features' don't exist (mostly because they aren't needed,
since iTP (running on NonStop) works fundamentally different).
NS/JSP is based on Tomcat and many HTML5 tools that rely on that and
AXIS should run well.
As always, some packages that depend on multiple threads running in a
shared memory space will not scale well and should be investigated on
a case-by-case basis.