That would depend on the particular module
if it is a pure python module then it will work anywhere
if it is a C module for example cStringIO then it would be architecture
dependent.
some modules are wrappers to external library's (example GTK) so for
those to work the necessary library files would need to be available
if you are using modules that are in the standard library (except some
platform specific ones ) then they should be available across all
platforms, otherwise you would need to check
see
http://docs.python/library for details of the standard library