It isn't clear to us what behavior you want to have from your mapping.
In the code you show, each of the variables is bound to a particular element
of your input list. So you can use them to reference the values of the list.
But each of the variables is a local variable inside the LET form, so any change
to the variable is just a local effect. It will not change the value in the input
list unless the change you make on the local variable is a mutation of the object
that the variable is bound to.
The code you provided should return the value of (+ A (- C B)). What do you
expect it to do?
Some other comments.
In general ELT is not a great function to use on lists, because it has to walk the
list until it gets to the Nth element. If you want to bind a number of variables to
elements of a list, then DESTRUCTURING-BIND will be more convenient and also
more efficient.
But if you have a fixed size list where the individual elements have some meaningful
names, then perhaps an even better approach would be to use a struct (via DEFSTRUCT)
to provide named accessors to the elements. It would also have the side benefit
of being both more space and time efficient.