Regardless of what control system you choose you will have a learning curve. How much of a curve will most likely depend on the complexity of the system you are integrating and your current skill level with programming concepts in general. For all but the most basic of systems, what you are asking for - simple drag and drop programming - doesn't really exist in any one system that is available today, in my opinion. There will always be something that one system does that another doesn't, or some device that you want to control that you can't find a driver for, at which point you are left to do the heavy lifting and create the driver/feature/function yourself. In my experience this is almost always the case regardless of the control system, and the more complex and custom the system gets, the further away from a drag and drop scenario you will find yourself. Since we don't know what you are trying to control (i.e. one TV and a satellite box, or 30 zones of audio and video distribution, security, HVAC and lighting integration, etc.) it is a pretty tough question to answer.
Having said that, my company currently uses Crestron with CommandFusion for most of our larger projects as the flexibility of the two combined allows us to get the results that we can't currently achieve using only one system. I'm sure that will change at some point as technology evolves. At this point in time there are things that I can't easily do in CommandFusion that I can do very rapidly in Crestron. There are also things I can do in CommandFusion that are for the most part impossible in Crestron. Some of the issues are hardware and some my own inability to achieve the desired results with one tool over the other mainly because of my experience level with each tool (15 years in Crestron, less than 2 years with CommandFusion).
I can tell you this - the support you will receive from this community and from the guys at CommandFusion is some of the best support in the industry and I'm sure that if you provide more details about what your end result looks like, someone here will probably help you make the best decision for you and your capabilities. Either way, I'm sure you'll get a lot of opinions :-) Good luck!!
Greg