Finding Stoichiometric imbalance

[Sreeram Chandra Murthy Peela]

Hi all.

I have just started learning metabolic modelling for bacterial genomes. I have used CarveMe for model generation and checked model consistency using Memote. However as per the memote report, the stoichiometric consistency is 0%. I would like to verify the same using CobraPy v0.29.0, but couldn't find the required function.

Can someone please share tutorial regarding model validation using CobraPy and the modules to be used? Thanks.

PS: I am a learning myself, and any help in this direction would be greatly appreciated.

[ronan.mt...@gmail.com]

Unless it has been changed recently, the implementation of stoich. consistency checking in Memote is erroneous. 

See https://academic.oup.com/bioinformatics/article/39/9/btad450/7269197