Can you compare the instability of ferritin observed with that of apoferritin
when there is no ferrihydrite core in the capsule? There are literature data on
apoferritin stability. For 'artificial ferritin' with magnetic nanoparticles
inside apoferritin (known as magnetoferritin), in addition to pH, the stability
of the protein shell strongly depends on magnetic loading [L. Melníková, et. al.
Coll. Surf. B 123 (2014) 82; Balejcíková L., et al., Coll. Surf. B 156 (2017)
375]. So, the role of the ferrihydrite core in your case is an
appropriate question.