Diwan Design 2023

[Edelmira Bendorf]

Asa main or auxiliary piece, the discretion and visual lightness of this design allows it to be adapted to the aesthetic needs of any interior design project, from the most minimal to the most eclectic. Diwan is a small and versatile range of seats from a daybed to an armchair, through a small divan or a large modular bench.

The benches can be used separately or joined to create long composations. Designed for sitting, rather than lounging, they have a higher seat height than the divan. The chaise loungues and armchairs provide greater support for more relaxed seating.

Diwan can function both in informal settings and in the most refined spheres, whether as a coquettish piece for the bedroom or to be enjoyed during long conversations with friends, as a bench for a museum or as a long composition for a large waiting area or as ancillary furniture in an office breakout area.

The Diwan pavilion is located on the edge of the garden, aligned symmetrically with the axes of the central court. Functionally, the building will provide an event space as well as a rooftop terrace overlooking the garden. In Punjabi, the term Diwan designates an event or meeting space.

The roof of the Diwan cantilevers over its base providing shade for visitors during sunny months. Above the entrance perforated metal panels were installed to screen dappled sunlight onto the surface and interior of the building.

Patterns for the screens, as well as mosaic floor and ceiling, were derived from motifs used in the garden. Although the project was constrained by a limited budget, the architects managed to emulate the design quality of the garden through a creative use of materials and fabrication techniques.

Computational drug design methods have great potential in drug discovery particularly in lead identification and lead optimization. 3-Phosphoinositide dependent kinase-1 (PDK1) is a protein kinase and a well validated anti-cancer target. Inhibitors of PDK1 have the potential to be developed as anti-cancer drugs. In this work, we have applied various novel computational drug design strategies to design and identify new PDK1 inhibitors with potential anti-cancer activity. We have pursued novel structure-based drug design strategies and identified a new binding mode for celecoxib and its derivatives binding with PDK1. This new binding mode provides a valuable basis for rational design of potent PDK1 inhibitors. In order to understand the structure-activity relationship of indolinone-based PDK1 inhibitors, we have carried out a combined molecular docking and three-dimensional quantitative structure-activity relationship (3D-QSAR) modeling study. The predictive ability of the developed 3D-QSAR models were validated using an external test set of compounds. An efficient strategy of the hierarchical virtual screening with increasing complexity was pursued to identify new hits against PDK1. Our approach uses a combination of ligand-based and structure-based virtual screening including shape-based filtering, rigid docking, and flexible docking. In addition, a more sophisticated molecular dynamics/molecular mechanics- Poisson-Boltzmann surface area (MD/MM-PBSA) analysis was used as the final filter in the virtual screening. Our screening strategy has led to the identification of a new PDK1 inhibitor. The anticancer activities of this compound have been confirmed by the anticancer activity assays of national cancer institute-developmental therapeutics program (NCI-DTP) using 60 cancer cell lines. The PDK1-inhibitor binding mode determined in this study may be valuable in future de novo drug design. The virtual screening approach tested and used in this study could also be applied to lead identification in other drug discovery efforts.

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The alluring year-round pavilion has won two international awards for its design: first in the category of Exposition Centres of the International Architecture Awards, and then gold certification in the category of Public Building / Cultural Building from Grand Prix Du Design.

The Diwan was inaugurated last September in a ceremony attended by Princess Zahra Aga Khan on behalf of her father, His Highness the Aga Khan and completes the Aga Khan Garden, which is the northernmost Islamic garden in the world and a contemporary interpretation of Islamic landscape architecture on the Canadian Prairies.

Inspired by traditions of Islamic building arts, the Diwan features geometric patterns, surfaces, and screens. Greeting guests as they approach the front entrance is a canopy marked by intricate metal screens serving as an interpretation of the traditional architectural element mashrabiya, which creates cast patterned shadows.

The Diwan was a collaboration of three firms: design architect AXIA Design Associates, architect-of-record Kasian Architecture Interior Design and Planning Ltd., and interiors by Arriz and Co. The space marks a landmark in a history of shared partnership between the Ismaili community and the University of Alberta. The Diwan can be booked by the public for events.

Bringing the concept of livability to life in real living spaces, Mada Residences offers 1, 2, 3, and 4-bedroom apartments located in the heart of Downtown Dubai. Each apartment has been meticulously designed with a focus on family-centric livability, catering to those who cherish spacious living areas. Featuring floor-to-ceiling glass windows, a private balcony in each apartment, and carefully planned amenities, our design maximizes space utility and delivers lasting value.

As a global organization operating in a global market, we at Dewan Architects + Engineers understand how important it is to recognize and champion the various backgrounds, life experiences, and cultures amongst our staff and within the communities we serve.

Diversity and inclusion are essential elements of our corporate culture. We strive to create a work environment that supports the success of all employees, attracts a diverse pool of applicants, and encourages people to build long-term careers at Dewan.

Participants were invited to submit their ideas for a Rehabilitation Centre for Terrorism Victims in Iraq. The rehabilitation Centre should offer a safe and comfortable space for the patients, supporting their health, psychological and physical needs.

Participants were asked to design a multi-activity youth complex and a public plaza in Almedina in Baghdad, creating a youthful cultural strip and a public platform that can host various cultural and social events. The Youth House, the plaza and their integration with each other and their surrounding context should inspire a transformation of the urban scene of Almedina.

Participants were asked to design a primary school in the long-forgotten area of the Iraqi marshes, taking into account the limitations of the area and the ecological impact of construction on nature and the fauna of the marshes. The design is for a 6-class primary school serving the nearby villages with all the amenities of a modern school.

"The term Diwan has varied historical definitions, and here implies a space for meeting, cultural exchange, and celebration," explained Toronto-based architecture studio AXIA Design Associates, which worked with fellow Toronto design studio Arriz + Co on the project.

"In addition to providing multi-use functionality, the pavilion was to resonate with its rich surroundings and extend the themes of the Garden, a contemporary interpretation of Islamic landscape architecture in a northern climate and context," said AXIA.

Other university campus projects include the renovation of Yale University's 120-year-old student centre by RAMSA and a proposed addition to the cole Polytechnique Fdrale de Lausanne by architects 3XN and Itten-Brechbhl.

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The NBW team was then given a full year to research the project, including travelling to the great Islamic gardens of Cairo, Jaipur, Delhi, and many more. In a moment of revelation outside Jaipur, Woltz envisaged the whole continuum of garden design stretching back to traditional methods of controlling and using water, right up to current issues of flood control, food insecurity and climate extremes. The task was not just to create a pleasure garden, he realized, but to reflect a history of the stewardship of productive landscapes. This approach could connect ancient practices, teachings and poetry with 21st-century life and issues in a way that both those of the Ismaili faith and all Canadians could understand.

The Aga Khan Garden CLIENT Aga Khan Trust for Culture LANDSCAPE ARCHITECT TEAM Thomas Woltz, Breck Gastinger, Nathan Foley, Sandra Nam Cioffi, Jen Trompetter, Alisha Savage, Siobhan Brooks, Fraser Stuart, Kari Roynesdal ARCHITECT Dialog Design CIVIL ISL Engineering and Land Services FOUNTAIN CMS Collaborative Inc. IRRIGATION Ion Irrigation Management Inc. DESIGN ENGINEER FTL Design Engineering Studio ENVIRONMENTAL Spencer AREA 10 acres BUDGET $763 K COMPLETION 2018

Groundwork is a three-part film and exhibition series exploring the conceptual development and field research of contemporary architects cultivating alternative modes of engagement with new project sites. Using documentary as

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