Introduction To Pharmacology Notes Pdf

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Paula Shuffleburg

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Aug 3, 2024, 6:08:52 PM8/3/24

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Using examples of commonly used drugs (both therapeutic and illicit), we will explore what drugs do to the human body and in turn, what the body does to drugs. Recommended for students with an interest in pursuing medical science degrees and programs. Prerequisites: CHEM 101 and BIOL 107 or equivalent. Open to 2nd and 3rd year students only.

Lecture topics present principles of pharmacology including practical application of commonly used drugs to the treatment of disease. This course is available only to students registered in the Bachelor of Science (Dental Hygiene) program.

This course is designed to introduce students to pharmacological research. The student will carry out an individual research project in a laboratory under the supervision of a member of the Department of Pharmacology. Supervision by Professors from other Departments may be possible, provided that a sponsor from the Department of Pharmacology is identified and the project is relevant to the discipline of Pharmacology. Students must secure a supervisor before registration. There may be a limited number of spaces available. The course offers formal opportunity to gain hands-on experience and develop skills within a research laboratory setting. Students will have a chance to become familiar with good lab practices, develop critical thinking, evaluation and troubleshooting skills, while applying their knowledge to practical research questions. Completion of this course requires a written report of the project and a presentation to an examining committee. Restricted to Pharmacology Honors or Specialization students in the third year of their program. Registration must be approved by the Department of Pharmacology. Please contact the course coordinator for registration in the course.

The adverse effects of xenobiotics on biological systems are discussed. Principles of toxicology are introduced. Responses of target organs to selected toxicants are described, with emphasis on molecular mechanisms. Special topics include chemical carcinogenesis, nanotoxicology, and endocrine disruptors. Prerequisites: PMCOL 200, BIOCH 200, PHYSL 210, or 212 and 214, or consent of Department.

An introduction to the complexities of drug abuse and the drugs of abuse. The student will be introduced to the psychological and social problems of drug abuse and their impact upon the abuser. Objectives of the course are to develop an understanding of addiction and a detailed knowledge of the nature of the commonly abused substances. Emphasis will be placed upon the pharmacology of drugs of abuse. Prerequisites: one of the following BIOCH 200, BIOL 201, CELL 201, PHYSL 210, PHSYL 212 and 214, PMCOL 200, PSYCH 275, ZOOL 241 and 242.

Study of factors that affect drug absorption, distribution, metabolism, and elimination (ADME). This includes an introduction to genetic factors that influence ADME of drugs, as well as practical exercises to illustrate pharmacokinetic principles and their relevance to therapeutic dosing. Drug-drug interactions and food-drug interactions will also be discussed. Prerequisites: PMCOL 200, BIOCH 200, PHYSL 210, or 212 and 214, or consent of Department.

Provides a hands-on experience in addressing basic pharmacological questions. The course will employ both in vitro techniques and behavioural models. Emphasis will be placed on experimental design and data collection, analysis and presentation. Normally restricted to third year Pharmacology Specialization or Honors students. Students not in these programs may be admitted via consent of the instructor if space is available.

This course, together with the subsequent PMCOL 344, provides a comprehensive study of the modern science of pharmacology. The objective of the course is to study how drugs act on physiological systems with an emphasis on therapeutic applications. This course may be especially useful to those students who wish to pursue a career in health sciences. Prerequisite: a 200-level PMCOL course or consent of instructor. Pre or corequisite: PHYSL 210, or 212 and 214, or consent of instructor. In the case of over subscription, preference will be given to students in the Pharmacology Specialization or Honors Programs.

A continuation of PMCOL 343, this course will examine the therapeutic application of a variety of drugs and the mechanism(s) by which they affect physiological systems. Pre or co-requisite: PHYSL 210, or 212 and 214, or consent of instructor. In the case of over subscription, preference will be given to students in the Pharmacology Specialization or Honors Programs.

Lectures presented by the Faculty of Medicine and Dentistry and the Faculty of Science on nerve cell membranes, ion channels, neurotransmitters and their receptors, synaptic mechanisms and plasticity, gene regulation and development, the physiology of small neural networks and disorders involving basic mechanisms. Prerequisite: PHYSL 210, or 212 and 214, or 252, or ZOOL 242. Students who have taken ZOOL 342 may not receive credit in PMCOL 371.

The student will carry out an individual research project in a laboratory under the supervision of a member of the Department of Pharmacology. Supervision by Professors from other Departments may be possible, provided that a sponsor from the Department of Pharmacology is identified and the project is relevant to the discipline of Pharmacology. Students must secure a supervisor before registration. The course offers formal opportunity to gain hands-on experience and develop skills within a research laboratory setting. Students will have a chance to become familiar with good lab practices, develop critical thinking, evaluation and troubleshooting skills, while applying their knowledge to practical research questions. Completion of this course requires a written report of the project and a presentation to an examining committee. Restricted to Pharmacology Specialization students or Honor students in Stream B in the fourth year of their program. Registration must be approved by the Department of Pharmacology. Please contact the course coordinator for registration in the course.

This course is designed to allow students to explore current topics and issues in pharmacology via projects such as critical literature reviews, simulated grant applications, community outreach and service projects. Before registration students must secure a supervisor from the Department of Pharmacology who will guide them through the course. Supervision by Professors from other Departments may be possible, provided that a sponsor from the Department of Pharmacology is identified and the project is relevant to the discipline of Pharmacology. Successful completion of a written report and a presentation is required at the conclusion of the project. Restricted to Pharmacology Specialization students or Honor students in Stream B in the fourth year of their program. Honors students in Stream B should consider enrolling in this course if they wish to focus within a singular Pharmacology topic but without the hands-on/lab experience. Prerequisites: PMCOL 303, PMCOL 306, PMCOL 343, PMCOL 344 or consent of instructor. Please contact the course coordinator for registration in the course.

Topics will include the drug discovery process, advanced concepts in pharmacodynamics and pharmacokinetics, the use of animal models of disease by the pharmaceutical industry, and therapeutic drug monitoring. Prerequisites: PMCOL 343 and PMCOL 344. In the case of over subscription, preference will be given to students in the Pharmacology Specialization or Honors Programs.

This course will present an overview of structure-based drug design, and delve into the molecular and structural factors that underlie drug affinity and efficacy. Concepts will be exemplified using receptor, ion channel, transporter, enzyme, and other protein families that represent important drug targets. Part of the course will be structured around the critical analysis of primary literature on related topics. Students will also have an opportunity to explore protein-drug interactions using molecular viewing software. Prerequisites: PMCOL 343, PMCOL 344, and PMCOL 306, BIOCH 320, or consent of Department.