Thetop 2 dogs from each race will move ahead in the competition to the Semifinals. A total of 20 corgis will advance to Semifinals, which are 2 races at the big main track.
Top 5 from each Semifinals race will advance to FINALS on the big main track, 1 RACE, 10 corgs- 1 WINNER!!!
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The dog is thought to be the first organism our ancestors artificially selected. Around 32,000 years ago, while our ancestors were still hunters and gatherers, wild wolves in East Asia joined groups of humans as scavengers. They were domesticated and then artificially selected to increase docility, leading to dogs that are closely related to what are currently known as Chinese native dogs [2]. Over millennia, various traits such as size, hair length, color and body shape were artificially selected for, altering the genetics of these domesticated descendants of wolves so much that we now have breeds such as Chihuahuas and corgis that barely resemble wolves at all! Since this time, artificial selection has been applied to many different species and has helped us develop all sorts of animals from prize-winning racehorses to muscular beef cattle.
Artificial selection has also been utilized with a variety of plants. The earliest evidence of artificial selection of plants dates back to 7800 BCE in archaeological sites found in southwest Asia, where scientists have found domestic varieties of wheat [3]. However, one of the most dramatic and prevalent alterations in plant genetics has occurred through artificial selection of corn. Corn, or maize, began as a wild grass called teosinte that had tiny ears with very few kernels [4]. Over the hundreds of years, teosinte was selectively bred to have larger and larger ears with more and more kernels, resulting in what we now know as corn. A similar process has given us large heads of broccoli, bananas with nearly unnoticeable seeds, and apples that are sweet and juicy.
An enormous breakthrough in GMO technology came in 1973, when Herbert Boyer and Stanley Cohen worked together to engineer the first successful genetically engineered (GE) organism [5]. The two scientists developed a method to very specifically cut out a gene from one organism and paste it into another. Using this method, they transferred a gene that encodes antibiotic resistance from one strain of bacteria into another, bestowing antibiotic resistance upon the recipient. One year later, Rudolf Jaenisch and Beatrice Mintz utilized a similar procedure in animals, introducing foreign DNA into mouse embryos [6].
Due to the unprecedented transparency and cooperation at the Asilomar Conference, government bodies around the world supported the move to continue with GE research, thus launching a new era of modern genetic modification.
In 1980, the U.S. Supreme Court of the ruled that scientists from General Electric could patent bacteria that were genetically engineered to break down crude oil to help with oil spill mitigation [10]. This ruling legally permitted ownership rights over GMOs, giving large companies the incentive to rapidly develop GMO tools that could both be useful and profitable.
Two years later, in 1982, the United States Food and Drug Administration approved the first human medication produced by a genetically modified organism. Bacteria had been genetically engineered to synthesize human insulin, allowing them to produce enough of the hormone to purify, package, and prescribe it to diabetes patients as the drug Humulin [11].
In addition to making food more aesthetically pleasing, scientists have developed crops that are easier to for farmers to cultivate. In 1995 the first pesticide-producing crop was approved by the U.S. Environmental Protection Agency after rigorous testing [12]. A year later, Bt corn was approved, and now the majority of corn in the U.S. has the Bt toxin gene (see this article). Additionally, crops have also been genetically engineered to resist herbicides, making it easier for farmers to control unwanted plants in their fields. Perhaps the most famous herbicide resistant crops are the Roundup Ready or glyphosate-resistant plants (see this article). The first of these glyphosate-resistant crops was a variety of soybean, engineered by Monsanto in 1996. Now glyphosate-resistant technology has been applied to many other crops, including corn and sugar beets.
Scientists have also genetically engineered crops to increase nutrition value. For instance, Golden Rice was developed in 2000 with the goal to combat vitamin A deficiency, which is estimated to kill over 500,000 people every year (see this article)[13].
Although many species of animals have been genetically engineered, the vast majority of this technology is used for research purposes, and to date, there have been no GE animals approved by the FDA for use in food production [14]. However, in 2009, the U.S. FDA approved the first biological product produced by a GE animal, ATryn, a drug used to treat a rare blood clotting disorder [15].
There have been many controversies regarding GE technology, with the majority relating to GE food. While some critics object to the use of this technology based on religious or philosophical bases, most critics object on the basis of environmental or health concerns. For instance, a 1999 publication showed Bt toxin had negative effects on butterfly populations in laboratory tests, leading to strong objections of Bt use, but follow-up studies in actual farming fields confirmed the safety of this technology [16]. In a different example, the economic stress of the poor yield of GE cotton crops in India over the late 1990s and early 2000s was associated by many organizations with a presumed increase in farmer suicides [17]. However, it was later concluded that suicide rates were actually unchanged after introduction of GE cotton, and that there were economic benefits of GE cotton for most Indian farmers [18].
During the same time frame, public awareness of the existence of GE foods increased, and calls for regulation of GE food grew louder, resulting in labeling requirements for GE food in many countries. Today, 64 countries have mandatory labeling laws for GE food [19]. However, the United States still does not have a mandatory, nationwide labeling law, although many advocacy groups are lobbying to enact one. These groups argue that labeling GE food is important for consumer choice and for monitoring unforeseen problems associated with the technology [20]. In contrast, groups opposing labels claim a law would unnecessarily eliminate consumer demand for current GE crops, causing steep increases in food price and resource utilization [20].
There are countless potential uses of GE technology in development. These include plants with superior disease and drought resistance, animals with enhanced growth properties, and strategies for more efficient pharmaceutical production [23]. Likewise, GE technology itself is quickly advancing. Recently, researchers have developed a new technology called CRISPR, which takes advantage of bacterial systems to simplify genetic editing, allowing for easier development of GE organisms [24]. This technology could be used to expedite development of useful GE crops, facilitate disease elimination, or even alter entire ecosystems. Interestingly, recent advances in plant breeding techniques may increase the utility and rebound the popularity of the more traditional GMO method of selective breeding. Indeed, new drought resistant strains of various crops have been recently developed using traditional breeding methods [25].
Wow! This was amazing! I was reading this for a research project and I was interested the whole time. It felt like something I truly wanted to red. This article was written so artfully and I adored how you pulled in the beginning statement/title at the end of your work. Thank you so much for publishing your work, it is so inspiring and I thoroughly enjoyed reading it!
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In a college environment, one of the most important things for students to learn how to do is to find positive and beneficial ways to deal with stress and stressful environments. In recent decades, studies have shown that one of the most effective ways to do this is to interact with therapy dogs. While such an option had long been unavailable for students at the College of William and Mary, thanks to Marisol Lambert, who herself graduated from the College in 1980, and her four corgis, Nellie, Louie, Tucker and Humphrey, students can meet professionally trained therapy dogs in Earl Gregg Swem Library every Friday at 2 p.m.
Whenever she would visit the College, she always brought her dogs with, and she observed the overwhelmingly positive reactions of the students who engaged with them. This gave her the idea to allow students to have an official opportunity to interact with the dogs.
Initially, Lambert had difficulties getting the dogs to be regularly allowed into the campus buildings, but the great impact she was having on the student body allowed her to come in with her corgis on a weekly basis.
Since coming to the College for therapy dog sessions in 2017, Lambert and her corgis have brightened the days of every student that comes and meets them. Just last semester she returned to visiting the College on a regular basis with her corgis. Lambert added that the times that stick out to her the most are when the corgis help a student who especially needs it.
Lambert and her four corgis have made an indescribable, positive impact on the College community, and they have no desire to stop helping the College in their weekly trips to the library. Lambert said that in the future, now that COVID-19 restrictions are loosening, she hopes to come to more events at the College so that she can help more students in any way possible.
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