Fwd: NDR-RT (US inter-agency drug compound taxonomy)

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Egon Willighagen

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Oct 18, 2010, 5:46:36 PM10/18/10
to cheminf-...@googlegroups.com, Eric Prud'hommeaux
Hi all,

has someone seen the NDR-RT ontology? If so, what are your experiences?

Egon

---------- Forwarded message ----------
From: Eric Prud'hommeaux <er...@w3.org>
Date: Fri, Oct 15, 2010 at 5:39 AM
Subject: NDR-RT (US inter-agency drug compound taxonomy)
To: egon.wil...@gmail.com


have you looked at NDF-RT? It's a drug compound taxonomy being
developed by a bunch of US government agencies: Department of Veterans
Affairs (VA), Food and Drug Administration (FDA), National Library of
Medicine (NLM), National Cancer Institute (NCI), Centers for Medicare
and Medicaid Services (CMS). What stuff in LODD covers this?

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl

--
-ericP

--
Dr E.L. Willighagen
Postdoctoral Research Associate
University of Cambridge
Homepage: http://egonw.github.com/
LinkedIn: http://se.linkedin.com/in/egonw
Blog: http://chem-bla-ics.blogspot.com/
PubList: http://www.citeulike.org/user/egonw/tag/papers

Janna Hastings

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Oct 21, 2010, 6:12:12 AM10/21/10
to cheminf-...@googlegroups.com, Eric Prud'hommeaux
Hi Egon,

I had once tried to investigate them in order to link up with ChEBI, but back then I was not able to find a good scheme for linking based on a shared ID annotation or a chemical structure representation. This was about two years ago and it is possible that it has improved a lot since then.

They have a good bioactivity-based classification and a strength is the model division into products, mechanisms of action, indications and ingredients. They do not, however, have chemical structures for their ingredients which reduces matching to name-based matching -- in some cases they have systematic names but in other cases just common names.

What is their licensing status, do you know? If it is the same as SNOMED then it is no good for us since it is not really open.

Cheers, Janna
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