Bit of a wild guess here as there isn't enough detail to work from - but what you're describing sounds like a browser content blocker may be responsible for stopping those links from loading/working.
You might find it helpful to share:
* What is the app (and any source code related to the errors)
* What environment you're testing this in (web browser, Powerchart, etc)
Other questions and insights are likely to follow with more information to work from.