Re: Studying Phosphorylation Levels

[Soumya Joshi]

I was also wondering if I could set up a meeting with someone who can help me understand the best way of studying and correlating abnormal mRNA expression levels for a set of genes?

On Wed, Mar 25, 2026 at 5:51 PM Soumya Joshi <sh...@scarletmail.rutgers.edu> wrote:

Hello,

I am studying a specific gene (LATS1 and LATS2), and I am trying to see the prevalence of phosphorylation (either general or at its N-terminus). I tried to query it using the special IDs template described in the FAQs, but it shows up as an error. How can I go about obtaining the data?

Thanks,

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Soumya Joshi

Rutgers Honors College '28

[Soumya Joshi]

[Nikolaus Schultz]

Hi,

I don’t think we have LATS1 or LATS2 phosphorylation data in cBioPortal. The CPTAC mass spec data only includes general protein levels, and the RPPA data in TCGA does not contain phospo-specific antibodies for these two proteins. As an example, see this correlation study of RPPA antibodies with LATS1 expression by mass spec: https://bit.ly/3NBWbDd

I hope this is helpful.

Niki.

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[Soumya Joshi]

Thanks for the information. Do you know of any dataset or database that I can use to study LATS phosphorylation in certain cancer types, ideally the same ones studied in the PanCancer studies?

Also, is it possible to set up a meeting with someone who can show me how best to visualize and compare mRNA expression levels between different groups of genes?