Good evening
Our group has worked on the METABRIC database for several years, since
its release.
In 2019 the database was incorporated in the cbioportal, but with less
samples , 1904 on Illumina v3 microarray, and less genes then the
original DB 35.655 probeset vs 24.368 gene/transcript.
Now in November 2022, but I noticed it only three days ago, the METABRIC
DB changed again, and now there are the original 1980 samples, and even
less genes (20.602 instead of 24.368 of the 1904 samples dataset).
I also noticed that several genes changed their level of expression and
that also the follow up for some patient has been updated.
Since I worked for three years on the 1904 samples dataset, for several
project in my lab, I would like to know, if possible, why and how you
changed the dataset.
And most important, if I should reanalyze all my data on this new
dataset (1980 samples, 20.602 genes) because it is the final and stable
version?
Thank you very much for any info you can give to me.
All the best
Stefano
--
Dr. Stefano Confalonieri
Senior Staff Scientist
Department of Experimental Oncology
European Institute of Oncology
Via Adamello 16, 20139 Milano, Italy
Phone:
+39 02 94372755
Mail:
stefano.co...@ieo.it
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