cBioPortal user reported error

[Ana Clara Carrera]

We clicked the CBIO search and we received this error, could you help us?

Yours, Ana Carrera

http://www.cbioportal.org/results/oncoprint?cancer_study_list=lusc_tcga_pan_can_atlas_2018&Z_SCORE_THRESHOLD=1.6&RPPA_SCORE_THRESHOLD=1.6&profileFilter=mutations%2Cstructural_variants%2Cgistic%2Crna_seq_v2_mrna_median_all_sample_ref_normal_Zscores%2Crppa_Zscores&case_set_id=lusc_tcga_pan_can_atlas_2018_all&gene_list=TRIM24&geneset_list=%20&tab_index=tab_visualize&Action=Submit;{"req":{"method":"POST","url":"//www.cbioportal.org/api/studies/fetch?projection=DETAILED","data":"[\"lusc_tcga_pan_can_atlas_2018\"]","headers":{"accept":"application/json","content-type":"application/json"}},"xhr":{"_url":"//www.cbioportal.org/api/studies/fetch?projection=DETAILED"},"text":"{\"timestamp\":1746788963517,\"status\":500,\"error\":\"Internal
Server
Error\",\"path\":\"/api/studies/fetch\"}","statusText":"","statusCode":500,"status":500,"statusType":5,"info":false,"ok":false,"redirect":false,"clientError":false,"serverError":true,"error":{"status":500,"method":"POST","url":"//www.cbioportal.org/api/studies/fetch?projection=DETAILED"},"created":false,"accepted":false,"noContent":false,"badRequest":false,"unauthorized":false,"notAcceptable":false,"forbidden":false,"notFound":false,"unprocessableEntity":false,"headers":{"cache-control":"no-cache,
no-store, max-age=0,
must-revalidate","connection":"keep-alive","content-encoding":"gzip","content-type":"application/json","date":"Fri,
09 May 2025 11:09:23
GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","transfer-encoding":"chunked","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"header":{"cache-control":"no-cache,
no-store, max-age=0,
must-revalidate","connection":"keep-alive","content-encoding":"gzip","content-type":"application/json","date":"Fri,
09 May 2025 11:09:23
GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","transfer-encoding":"chunked","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"type":"application/json","links":{},"body":{"timestamp":1746788963517,"status":500,"error":"Internal
Server Error","path":"/api/studies/fetch"}}

--
Ana C. Carrera
Department of Immunology and Oncology, Lab413
Centro Nacional de Biotecnologia, CSIC
(National Biotechnology Centre, CSIC)
Darwin 3
Cantoblanco
Madrid 28049, Spain
acar...@cnb.csic.es
Tel: 3491-585-4846 o 34-699340094
Fax: 3491-3720493
http://www.cnb.csic.es/index.php/es/investigacion/departamentos-de-investigacion/inmunologia-y-oncologia/dianas-moleculares-para-cancer-e-inflamacion-enfoque-en-pi3-quinasa
https://carreraslab.wordpress.com/scientific-profile/

[Live.com]

https://www.cbioportal.org/;{"req":{"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL","data":"[\"NRP1\",\"EGFR\"]","headers":{"accept":"application/json","content-type":"application/json"}},"xhr":{"_url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"text":"{\"timestamp\":1746796358132,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/genes/fetch\"}","statusText":"","statusCode":500,"status":500,"statusType":5,"info":false,"ok":false,"redirect":false,"clientError":false,"serverError":true,"error":{"status":500,"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"created":false,"accepted":false,"noContent":false,"badRequest":false,"unauthorized":false,"notAcceptable":false,"forbidden":false,"notFound":false,"unprocessableEntity":false,"headers":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:12:38 GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"header":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:12:38 GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"type":"application/json","links":{},"body":{"timestamp":1746796358132,"status":500,"error":"Internal Server Error","path":"/api/genes/fetch"}}


{"req":{"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL","data":"[\"NRP1\",\"EGFR\",\"MET\",\"ERRB2\",\"BRAF\"]","headers":{"accept":"application/json","content-type":"application/json"}},"xhr":{"_url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"text":"{\"timestamp\":1746796376135,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/genes/fetch\"}","statusText":"","statusCode":500,"status":500,"statusType":5,"info":false,"ok":false,"redirect":false,"clientError":false,"serverError":true,"error":{"status":500,"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"created":false,"accepted":false,"noContent":false,"badRequest":false,"unauthorized":false,"notAcceptable":false,"forbidden":false,"notFound":false,"unprocessableEntity":false,"headers":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:12:56 GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"header":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:12:56 GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"type":"application/json","links":{},"body":{"timestamp":1746796376135,"status":500,"error":"Internal Server Error","path":"/api/genes/fetch"}}

[Luigi Catanzariti]

Hi,

Since yesterday, when I enter gene symbols in a query, I’m getting the error message below.

Thanks for your help.

Luigi Catanzariti


https://www.cbioportal.org/;{"req":{"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL","data":"[\"EGFR\",\"MET\",\"NRP1\"]","headers":{"accept":"application/json","content-type":"application/json"}},"xhr":{"_url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"text":"{\"timestamp\":1746797412560,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/genes/fetch\"}","statusText":"","statusCode":500,"status":500,"statusType":5,"info":false,"ok":false,"redirect":false,"clientError":false,"serverError":true,"error":{"status":500,"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"created":false,"accepted":false,"noContent":false,"badRequest":false,"unauthorized":false,"notAcceptable":false,"forbidden":false,"notFound":false,"unprocessableEntity":false,"headers":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:30:12 GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"header":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:30:12 GMT","elapsed-time":"0","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"type":"application/json","links":{},"body":{"timestamp":1746797412560,"status":500,"error":"Internal Server Error","path":"/api/genes/fetch"}}


Sent from my iPad

[Live.com]

https://www.cbioportal.org/;{"req":{"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL","data":"[\"EGFR\",\"NRP1\",\"MET\",\"ERRB2\",\"BRAF\",\"KEAP1\",\"NFE2L2\"]","headers":{"accept":"application/json","content-type":"application/json"}},"xhr":{"_url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"text":"{\"timestamp\":1746796205880,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/genes/fetch\"}","statusText":"","statusCode":500,"status":500,"statusType":5,"info":false,"ok":false,"redirect":false,"clientError":false,"serverError":true,"error":{"status":500,"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"created":false,"accepted":false,"noContent":false,"badRequest":false,"unauthorized":false,"notAcceptable":false,"forbidden":false,"notFound":false,"unprocessableEntity":false,"headers":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:10:05 GMT","elapsed-time":"1","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"header":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:10:05 GMT","elapsed-time":"1","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"type":"application/json","links":{},"body":{"timestamp":1746796205880,"status":500,"error":"Internal Server Error","path":"/api/genes/fetch"}}

[Tali Mazor]

Hi Ana,

Thanks for reaching out. We were experiencing some technical issues but they are now resolved. Please let us know if you continue to see any errors.

-Tali

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[Tali Mazor]

Hi Luigi,

Thanks for reaching out. We were experiencing some technical issues but they are now resolved. Please let us know if you continue to see any errors.

-Tali

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[Tali Mazor]

Hi,

Thanks for reaching out. We were experiencing some technical issues but they are now resolved. Please let us know if you continue to see any errors.

-Tali

On Fri, May 9, 2025 at 2:05 PM Live.com <luigi.ca...@gmail.com> wrote:

https://www.cbioportal.org/;{"req":{"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL","data":"[\"EGFR\",\"NRP1\",\"MET\",\"ERRB2\",\"BRAF\",\"KEAP1\",\"NFE2L2\"]","headers":{"accept":"application/json","content-type":"application/json"}},"xhr":{"_url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"text":"{\"timestamp\":1746796205880,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/genes/fetch\"}","statusText":"","statusCode":500,"status":500,"statusType":5,"info":false,"ok":false,"redirect":false,"clientError":false,"serverError":true,"error":{"status":500,"method":"POST","url":"//www.cbioportal.org/api/genes/fetch?geneIdType=HUGO_GENE_SYMBOL"},"created":false,"accepted":false,"noContent":false,"badRequest":false,"unauthorized":false,"notAcceptable":false,"forbidden":false,"notFound":false,"unprocessableEntity":false,"headers":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:10:05 GMT","elapsed-time":"1","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"header":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Fri, 09 May 2025 13:10:05 GMT","elapsed-time":"1","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"type":"application/json","links":{},"body":{"timestamp":1746796205880,"status":500,"error":"Internal Server Error","path":"/api/genes/fetch"}}

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[博禹]

https://www.cbioportal.org/study/plots?id=coadread_tcga&plots_horz_selection=%7B%22dataType%22%3A%22clinical_attribute%22%2C%22selectedDataSourceOption%22%3A%22FRACTION_GENOME_ALTERED%22%2C%22logScale%22%3A%22true%22%7D&plots_vert_selection=%7B%22dataType%22%3A%22clinical_attribute%22%2C%22selectedDataSourceOption%22%3A%22VASCULAR_INVASION_INDICATOR%22%2C%22logScale%22%3A%22true%22%7D&plots_coloring_selection=%7B%7D;{"type":"ErrorBoundary","log":"NotFoundError: Failed to execute 'removeChild' on 'Node': The node to be removed is not a child of this node."}

[Holly Henderson]

Hi,

I am trying to compare survival between different mutants types of a gene in all prostate cancer data sets but keep getting this error.

https://www.cbioportal.org/results/comparison/alterations?cancer_study_list=prad_mich%2Cprad_su2c_2019%2Cprad_su2c_2015%2Cprad_mcspc_mskcc_2020%2Cnepc_wcm_2016%2Cprad_broad_2013%2Cprad_broad%2Cprad_cpcg_2017%2Cprad_fhcrc%2Cprad_mskcc%2Cprad_pik3r1_msk_2021%2Cprad_cdk12_mskcc_2020%2Cprad_mskcc_2014%2Cprad_p1000%2Cprad_eururol_2017%2Cprad_tcga_pub%2Cprad_tcga%2Cprad_tcga_gdc%2Cprad_tcga_pan_can_atlas_2018%2Cprad_mskcc_cheny1_organoids_2014%2Cprostate_dkfz_2018%2Cprostate_msk_2024%2Cprad_msk_2019%2Cprad_mskcc_2017%2Cprad_organoids_msk_2022%2Cprostate_pcbm_swiss_2019%2Cprad_msk_mdanderson_2023%2Cprad_msk_stopsack_2021%2Cmpcproject_broad_2021&Z_SCORE_THRESHOLD=2.0&RPPA_SCORE_THRESHOLD=2.0&profileFilter=mutations%2Cstructural_variants%2Ccna%2Cgistic&case_set_id=all&gene_list=KMT2D&geneset_list=%20&tab_index=tab_visualize&Action=Submit;{"req":{"method":"POST","url":"//www.cbioportal.org/api/column-store/alteration-enrichments/fetch?enrichmentType=SAMPLE","data":{},"headers":{"accept":"application/json","content-type":"application/json","content-encoding":"gzip"}},"xhr":{"_url":"//www.cbioportal.org/api/column-store/alteration-enrichments/fetch?enrichmentType=SAMPLE"},"text":"{\"timestamp\":1747486086713,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/column-store/alteration-enrichments/fetch\"}","statusText":"","statusCode":500,"status":500,"statusType":5,"info":false,"ok":false,"redirect":false,"clientError":false,"serverError":true,"error":{"status":500,"method":"POST","url":"//www.cbioportal.org/api/column-store/alteration-enrichments/fetch?enrichmentType=SAMPLE"},"created":false,"accepted":false,"noContent":false,"badRequest":false,"unauthorized":false,"notAcceptable":false,"forbidden":false,"notFound":false,"unprocessableEntity":false,"headers":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Sat, 17 May 2025 12:48:06 GMT","elapsed-time":"1","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"header":{"cache-control":"no-cache, no-store, max-age=0, must-revalidate","content-encoding":"gzip","content-type":"application/json","date":"Sat, 17 May 2025 12:48:06 GMT","elapsed-time":"1","expires":"0","pragma":"no-cache","strict-transport-security":"max-age=31536000; includeSubDomains","vary":"origin,access-control-request-method,access-control-request-headers,accept-encoding","x-content-type-options":"nosniff","x-frame-options":"DENY","x-xss-protection":"0"},"type":"application/json","links":{},"body":{"timestamp":1747486086713,"status":500,"error":"Internal Server Error","path":"/api/column-store/alteration-enrichments/fetch"}}

[Aaron L]

Hi Holly, 

We should have this fixed in the next hour.  Thanks for the alert.

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[Lafaure Rachel]

Bonjour,

 

Je me permet de vous contacter suite à un message d’erreur que j’ai depuis quelques jours et qui m’empêche d’effectuer des recherches. Auriez-vous des informations ?

 

Merci d’avance, en vous souhaitant une bonne journée.

 

LAFAURE Rachel

 

 

https://www.cbioportal.org/results/mutations?case_set_id=all&gene_list=CMPK1&cancer_study_list=5c8a7d55e4b046111fee2296;{"type":"ErrorBoundary","log":"NotFoundError: Failed to execute 'removeChild' on 'Node': The node to be removed is not a child of this node."}

 

{"type":"ErrorBoundary","log":"NotFoundError: Failed to execute 'removeChild' on 'Node': The node to be removed is not a child of this node.","url":"https://www.cbioportal.org/results/mutations?case_set_id=all&gene_list=CMPK1&cancer_study_list=5c8a7d55e4b046111fee2296"}

[de Bruijn, Ino]

Hi Rachel,

 

Do you still see this issue?

 

Thanks!

Ino

 

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