survival analysis

[Mark Paris]

Hello.  I wonder if you can help me with an analysis.  I want to use kaplan meier analysis within squamous lung comparing two groups expressing protein X differentially (2X difference at protein is ideal, but mRNA could be OK).  I know how to select the studies.  I know how to query by gene.  Within the subsequent analysis page I can select "comparison/survival" but then I'm stuck.  Not sure where to go from there.  Thanks for the help.

Mark

[JJ Gao]

Hi Mark,

One option is to use the Gene Specific charts on the study view page (e.g. https://www.cbioportal.org/study/summary?id=lusc_tcga_pan_can_atlas_2018). You can add your genes of interest and show the chart for protein and mRNA expression. From there you can compare groups including your own custom bins/groups.

I hope this can address your question. Please feel free to contact us if you have any additional questions.

On Mon, Jun 1, 2026 at 4:59 PM Mark Paris <par...@gmail.com> wrote:

Hello.  I wonder if you can help me with an analysis.  I want to use kaplan meier analysis within squamous lung comparing two groups expressing protein X differentially (2X difference at protein is ideal, but mRNA could be OK).  I know how to select the studies.  I know how to query by gene.  Within the subsequent analysis page I can select "comparison/survival" but then I'm stuck.  Not sure where to go from there.  Thanks for the help.

Mark

--
You received this message because you are subscribed to the Google Groups "cBioPortal for Cancer Genomics Discussion Group" group.
To unsubscribe from this group and stop receiving emails from it, send an email to cbioportal+...@googlegroups.com.
To view this discussion visit https://groups.google.com/d/msgid/cbioportal/CAP6t9xpk9oF%3Dd9yEGqnx_85pw9qyHUx1CM-k%2BnRdWy5YxmAimQ%40mail.gmail.com.

[JJ Gao]

Hi Mark,

No apologies needed :). You might find this tutorial video be helpful: https://youtu.be/YUxVv6pkxD4?t=2396

Please feel free to reach out if you have additional questions.

Best,

-JJ

On Thu, Jun 4, 2026 at 6:50 PM Mark Paris <par...@gmail.com> wrote:

Thank you.  Very sorry, but I don't understand how that gets me to a KM curve by bin.

[JJ Gao]

You're welcome. Glad that it was helpful.

On Fri, Jun 5, 2026 at 12:50 PM Mark Paris <par...@gmail.com> wrote:

That's awesome!  Will explore but it appears to be exactly what I need.  THANK YOU!

Mark