How do I see in which exon a particular mutation falls into

[Elie Dib]

Hello,

If I look at EGFR mutations, I can see where the mutations happen in the protein. How can I find out to which corresponding exon each mutation falls into? Please look at the following link:

https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&Z_SCORE_THRESHOLD=2.0&RPPA_SCORE_THRESHOLD=2.0&profileFilter=mutations%2Cstructural_variants%2Ccna&case_set_id=msk_impact_2017_cnaseq&gene_list=EGFR&geneset_list=%20&tab_index=tab_visualize&Action=Submit

Thanks,

Elie

[Jessica Singh]

Hi Elie, 

cBioPortal allows you to add additional columns to the Mutations table under the Lollipop Plot. Click on the "Columns" button and add Exons from the drop-down list. See the screenshot below: 

Let me know if you have any further questions. 

Regards, 

Jessica

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[Nikolaus Schultz]

You can also show exon numbers as an annotation truck below the domain diagram.

Click on “Add annotation tracks” in the top left and search for “Exon”.

Niki.

On Sep 13, 2022, at 2:47 AM, Jessica Singh <jes...@thehyve.nl> wrote:

Hi Elie, 

cBioPortal allows you to add additional columns to the Mutations table under the Lollipop Plot. Click on the "Columns" button and add Exons from the drop-down list. See the screenshot below: 

To view this discussion on the web visit https://groups.google.com/d/msgid/cbioportal/CACK540MjLy68sfN6W0CCMPkZ0zQftGz3ORNduaC%2B3WpuaTEVbg%40mail.gmail.com.