Lollipop of APC starts at exon 2 instead of exon 1

[Aula Ammar]

Hello,

 

I am trying to generate a lollipop for APC however I am not sure why the lollipop map starts at exon 2-16 instead of 1-15? The gene should have 15 exons but I am not sure why it is coming up like that.

It would be great if you can let me know how to fix this. I tried that with your data and with my data but I am always getting exons 2-16 .

 

A screen shot is shown below

Thanks

Aula

 

 

[Nikolaus Schultz]

Hi Aula,

The first exon of the APC isoform used in cBioPortal is non-coding. The start codon is in exon 2, which is why that is the first exon shown in this protein diagram. 

Niki.

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[Aula Ammar]

Hi Niki,

 

Thanks a lot for the clarification!

 

Kind Regards

Aula