cbioportal access error

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Ng, Yuen-Keng

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Jul 8, 2025, 4:49:29 PM7/8/25
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Dear cbioportal support,
 
When I try to query the Cancer Cell Line Encyclopedia data set  (Broad, 2019) by gene via the cbioportal
 
Is the server/the cbioportal webpage  down for maintenance today as
I got the following error:
 
"{\"req\":{\"method\":\"GET\",\"url\":\"//www.cbioportal.org/api/studies/ccle_broad_2019/significantly-mutated-genes\",\"headers\":{\"accept\":\"application/json\"}},\"xhr\":{\"_url\":\"//www.cbioportal.org/api/studies/ccle_broad_2019/significantly-mutated-genes\"},\"text\":\"{\\\"timestamp\\\":1752002435411,\\\"status\\\":500,\\\"error\\\":\\\"Internal Server Error\\\",\\\"path\\\":\\\"/api/studies/ccle_broad_2019/significantly-mutated-genes\\\"}\",\"statusText\":\"\",\"statusCode\":500,\"status\":500,\"statusType\":5,\"info\":false,\"ok\":false,\"redirect\":false,\"clientError\":false,\"serverError\":true,\"error\":{\"status\":500,\"method\":\"GET\",\"url\":\"//www.cbioportal.org/api/studies/ccle_broad_2019/significantly-mutated-genes\"},\"created\":false,\"accepted\":false,\"noContent\":false,\"badRequest\":false,\"unauthorized\":false,\"notAcceptable\":false,\"forbidden\":false,\"notFound\":false,\"unprocessableEntity\":false,\"headers\":{\"cache-control\":\"no-cache, no-store, max-age=0, must-revalidate\",\"content-encoding\":\"gzip\",\"content-type\":\"application/json\",\"date\":\"Tue, 08 Jul 2025 19:20:35 GMT\",\"elapsed-time\":\"0\",\"expires\":\"0\",\"pragma\":\"no-cache\",\"strict-transport-security\":\"max-age=31536000; includeSubDomains\",\"vary\":\"origin,access-control-request-method,access-control-request-headers,accept-encoding\",\"x-content-type-options\":\"nosniff\",\"x-firefox-spdy\":\"h2\",\"x-frame-options\":\"DENY\",\"x-xss-protection\":\"0\"},\"header\":{\"cache-control\":\"no-cache, no-store, max-age=0, must-revalidate\",\"content-encoding\":\"gzip\",\"content-type\":\"application/json\",\"date\":\"Tue, 08 Jul 2025 19:20:35 GMT\",\"elapsed-time\":\"0\",\"expires\":\"0\",\"pragma\":\"no-cache\",\"strict-transport-security\":\"max-age=31536000; includeSubDomains\",\"vary\":\"origin,access-control-request-method,access-control-request-headers,accept-encoding\",\"x-content-type-options\":\"nosniff\",\"x-firefox-spdy\":\"h2\",\"x-frame-options\":\"DENY\",\"x-xss-protection\":\"0\"},\"type\":\"application/json\",\"links\":{},\"body\":{\"timestamp\":1752002435411,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/studies/ccle_broad_2019/significantly-mutated-genes\"}}\n\n\n{\"req\":{\"method\":\"GET\",\"url\":\"//www.cbioportal.org/api/studies/ccle_broad_2019/significant-copy-number-regions\",\"headers\":{\"accept\":\"application/json\"}},\"xhr\":{\"_url\":\"//www.cbioportal.org/api/studies/ccle_broad_2019/significant-copy-number-regions\"},\"text\":\"{\\\"timestamp\\\":1752002435487,\\\"status\\\":500,\\\"error\\\":\\\"Internal Server Error\\\",\\\"path\\\":\\\"/api/studies/ccle_broad_2019/significant-copy-number-regions\\\"}\",\"statusText\":\"\",\"statusCode\":500,\"status\":500,\"statusType\":5,\"info\":false,\"ok\":false,\"redirect\":false,\"clientError\":false,\"serverError\":true,\"error\":{\"status\":500,\"method\":\"GET\",\"url\":\"//www.cbioportal.org/api/studies/ccle_broad_2019/significant-copy-number-regions\"},\"created\":false,\"accepted\":false,\"noContent\":false,\"badRequest\":false,\"unauthorized\":false,\"notAcceptable\":false,\"forbidden\":false,\"notFound\":false,\"unprocessableEntity\":false,\"headers\":{\"cache-control\":\"no-cache, no-store, max-age=0, must-revalidate\",\"content-encoding\":\"gzip\",\"content-type\":\"application/json\",\"date\":\"Tue, 08 Jul 2025 19:20:35 GMT\",\"elapsed-time\":\"0\",\"expires\":\"0\",\"pragma\":\"no-cache\",\"strict-transport-security\":\"max-age=31536000; includeSubDomains\",\"vary\":\"origin,access-control-request-method,access-control-request-headers,accept-encoding\",\"x-content-type-options\":\"nosniff\",\"x-firefox-spdy\":\"h2\",\"x-frame-options\":\"DENY\",\"x-xss-protection\":\"0\"},\"header\":{\"cache-control\":\"no-cache, no-store, max-age=0, must-revalidate\",\"content-encoding\":\"gzip\",\"content-type\":\"application/json\",\"date\":\"Tue, 08 Jul 2025 19:20:35 GMT\",\"elapsed-time\":\"0\",\"expires\":\"0\",\"pragma\":\"no-cache\",\"strict-transport-security\":\"max-age=31536000; includeSubDomains\",\"vary\":\"origin,access-control-request-method,access-control-request-headers,accept-encoding\",\"x-content-type-options\":\"nosniff\",\"x-firefox-spdy\":\"h2\",\"x-frame-options\":\"DENY\",\"x-xss-protection\":\"0\"},\"type\":\"application/json\",\"links\":{},\"body\":{\"timestamp\":1752002435487,\"status\":500,\"error\":\"Internal Server Error\",\"path\":\"/api/studies/ccle_broad_2019/significant-copy-number-regions\"}}"
 
Thank you so much.
 
Best regards,
 
Yuen-Keng NG, PhD
Senior Research Scientist
Georgia Cancer Center
CN-3115, 1410 Laney Walker Blvd.
Augusta, GA 30912
 
 
 

Tali Mazor

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Jul 8, 2025, 4:56:07 PM7/8/25
to Ng, Yuen-Keng, cbiop...@googlegroups.com
Hi Yuen-Keng,

Thanks for reaching out. Can you please try again? We were having some issues with the site earlier today, but it's working now, and I am able to access the CCLE Broad 2019 study.

-Tali




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