Some colleagues and I have been troubleshooting crashes we see on our own instance of cBioPortal.
When using Chrome to query a highly mutated gene on a fairly large dataset (~28,000 samples corresponding to ~35,000 alterations), Chrome will hang at the "Annotating with OncoKB and Cancer Hotspots" for ~3-4 minutes. It will then just freeze, or display a mostly blank page (still has some of the header images and tabs, but no actual oncoprint). Monitoring the network requests within the browser shows one of the 'fetch' steps as "(failed)"
However, Firefox consistently returns results for the same query.
Performing a query with a less mutated gene (~28,000 samples corresponding to ~23,000 alterations), returns results in both browsers no problem.
Has anyone experienced a similar issue? Are there any ideas why Chrome might fail here? Please let me know if I can provide any more information that would be helpful (or if it would be better to post this as an issue on GitHub).
Thanks so much,