Hi,
I was comparing your bigWigs from the human brain atlas to our data generated in house, as well as to your human enhancer atlas data, and found that in the human brain atlas your bigwigs are essentially missing mapped reads for every celltype for a large locus around the gene FAN1. (An easy example to compare is Oligodendrocytes from both of your datasets or Microglia)
All the best,
Matthew Baffuto
Laboratory of Molecular Biology
The Rockefeller University