In this study, the effects of the exterior wall insulation thickness, glass feature and design temperature on the cooling capacity of the building were investigated mathematically and statistically by using an energy analysis program for a sample building in Ankara climate conditions. With these changed parameters, annual cooling loads were calculated and a mathematical model was created. Analyzes were simulated using the hourly analysis program (Carrier HAP) offered by the Carrier company. The importance of the created model was examined by performing analysis of variance (ANOVA) and the p-value was less than 0.05. This shows that the model is reliable. The model was validated and the error rate was found to vary between -0.27 and 0.26. It has been concluded that the minimum cooling capacity for the sample structure will be obtained if the wall heat transmission coefficient varies between 0.46 and 1.03, and the glass heat transmission coefficient varies between 2.48 and 3.7.