Re: tumor purity estimation by Canopy

[Jiang, Yuchao]

Hi Jinxiong,

Thanks for your interest in Canopy. The tumor purity is 1-the percentage of normal cells, and the normal cells by default is the first clone in the reconstructed tree.

I hope that this is helpful.
Yuchao

> On Apr 15, 2021, at 11:25 PM, 吕晋雄 <lvjin...@sjtu.edu.cn> wrote:
>
> Dear Prof. Jiang,
>
> My name is Jinxiong Lv, and I have been investigating the ITH-related methods. I found that the Canopy does not need tumor purity as input. How does Canopy conduct the estimation of tumor purity?
>
> Best wishes.
>
> Jinxiong Lv