Hi Dominik,
I haven't tried myself, and PyScript is definitely interesting. But as far as I
know, either you use the full Python implementation and the blob to download
is huge, or you use the Micropython version which is really small, but then
you loose the full and recent versions Python compatibility.
Brython on the other hand target full Python compatibility, and the size of
the files to download can be reasonable.
In my personal use case (where I want to use some modules both in backend and
frontend), Brython seems the only choice. It's a good one in any case, I'm
really happy with it :)
Regards,
Goffi