Got Your Shots? News: October 2025

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Minnesota Department of Health

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Oct 30, 2025, 10:11:47 AM (8 days ago) Oct 30
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Minnesota Department of Health

Got Your Shots? News

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October 30, 2025

In This Edition


Preventable but persistent: Travel keeps measles in circulation

Measles has continued to increase globally as well as nationally, with more than 1,600 cases reported in the United States in 2025. Minnesota has reported a total of 18 cases of measles in the past two months, bringing the state’s yearly total to 23. The most recent cases have occurred in unvaccinated people, and all have been connected to travel or to someone who had recently traveled:

  • Ten cases, all unvaccinated, were part of a cluster of cases that started when someone with measles had visited from another state.
  • Five cases occurred across three unrelated families who had unvaccinated family members exposed during the same international travel.
  • Three cases occurred in one family after recent international travel.

Cases have ranged from 1 to 21 years of age, and are residents of Dakota, Hennepin, Olmsted, Ramsey, and Washington counties. Multiple settings have been impacted by potential exposures while cases were infectious including schools, child care, health care, and other public settings. To stay current on cases, visit Measles Disease Statistics and CDC: Measles Cases and Outbreaks.

MMR vaccine is the best tool for fighting measles

Measles, mumps, and rubella are serious diseases that can individually cause severe complications such as pneumonia, encephalitis, hearing loss, and, in the case of rubella, birth defects during pregnancy. MMR vaccine continues to be the best tool for preventing measles. It has been in use for more than 50 years and has an excellent safety record. The standard two-dose series, the first at 12 to 15 months and second at 4 to 6 years, provides around 97% lifelong protection against measles and strong, durable protection against mumps and rubella.

For all ages, it is important to assess MMR vaccination status at every visit but especially for patients traveling internationally (including Canada and Mexico) or to an area of the U.S. experiencing an outbreak. Children 6 to 12 months old can get an early dose of MMR vaccine if their travels will put them at high risk for measles. This early dose does not count toward the two-dose series completion.

For information on measles disease, healthy travel, measles vaccine, and informational videos on the MMR vaccine, review the following resources:


ACIP updates

Acting Centers for Disease Control and Prevention (CDC) Director Jim O’Neill officially adopted the COVID-19 and MMRV immunization recommendations from the September meeting of the Advisory Committee on Immunization Practices (ACIP). These recommendations are now reflected in the updated immunization schedules CDC: Child and Adolescent Immunization Schedule by Age (Addendum updated August 7, 2025) and CDC: Adult Immunization Schedule by Age (Addendum updated August 7, 2025).

COVID-19 vaccine

The CDC recommends COVID-19 vaccination for people 6 months of age and older based on shared clinical decision making (SCDM) with emphasis on risks vs. benefits (CDC: ACIP Shared Clinical Decision-Making Recommendations and CDC: Underlying Conditions and the Higher Risk for Severe COVID-19). This recommendation ensures access to COVID-19 vaccine for children 6 months of age and older through the Minnesota Vaccines for Children (MnVFC) program.

The Minnesota Department of Health (MDH) endorses the more specific and evidence-based COVID-19 vaccine recommendations of the American Academy of Pediatrics (AAP), American Academy of Family Physicians (AAFP), Infectious Diseases Society of America (IDSA) and the American College of Obstetricians and Gynecologists (ACOG). For more information on MDH’s COVID-19 vaccine recommendations and protocols visit COVID-19 Vaccine Access for Minnesotans and Immunization Best Practices.

COVID-19 Vaccine Information Statement (VIS)

Continue to use the COVID-19 VIS dated 1/31/2025 until a new one is published. Never withhold a vaccine because there is not a current VIS for it. Using the existing version and verbally relaying pertinent updates is acceptable. To find the most updated versions, visit Current VISs or sign up to receive notifications on What’s New with VISs.

Measles, mumps, rubella and varicella (MMRV) vaccine

The CDC now recommends that children under 4 years of age should receive the measles, mumps, rubella (MMR) and varicella (chickenpox) vaccines as separate doses rather than the combined MMRV product (Proquad). This change impacts the availability of MMRV for children under 4 years of age within the MnVFC program.

MMRV vaccine remains licensed for 12 months to 12 years of age. Both the AAP and AAFP state that MMRV vaccine may be used for children under 4 years of age. For more information refer to AAP-Immunization-Schedule (PDF) and AAFP: Birth Through Age 18 Immunization Schedule.


MnVFC COVID-19 vaccine shipping now

MnVFC COVID-19 vaccine for the 2025-26 season started shipping earlier this month, and we continue to ship orders as doses become available from the manufacturers. MnVFC enrolled providers can submit additional requests for doses at any time in MIIC. For information on recommendations, schedules, and other resources, visit COVID-19 Vaccine Providers.

Now is the time to vaccinate against flu!

During the 2024-25 respiratory season, 281 children died from influenza in the United States. Most of those children were unvaccinated. Vaccination against influenza reduces the risk of severe illness, hospitalization, and death. Families Fighting Flu has posted a new video that highlights 7-year-old Kaden Stevenson’s battle against influenza called Kaden Blaze - Families Fighting Flu. It also features a new comic book and a library of digital and print resources inspired by Kaden’s story as well as many other resources that can be used to promote the importance of flu vaccine.

The Association for Immunization Managers (AIM) also has Flu Resources with updated educational resources about the flu vaccine including a one-page resource guide designed to provide program support related to health education, health communication and program planning.


Pediatric influenza-associated and acute necrotizing encephalopathy

Influenza-associated encephalitis (IAE), including acute necrotizing encephalopathy (ANE), is a rare complication following influenza infection, characterized by high fever, obtundation (changes in consciousness), seizures, and necrotic lesions in the brain. Due to increased reports of this condition in children during the 2024-25 influenza season, CDC released a call for pediatric cases to further understand IAE, including risk factors for children developing this complication. CDC, in partnership with state public health jurisdictions, including MDH, analyzed data from reported cases of IAE and ANE in the U.S. Of 109 pediatric IAE cases identified, 55% were previously healthy, and only 16% had received a current seasonal influenza vaccine.

One case of influenza-associated ANE was identified in Minnesota during the 2024-25 season in a child under 2 years of age who resides in the Twin Cities metro and has fully recovered.


RespSafe registration is now open

RespSafe registration is now open for Minnesota hospitals and long-term care (LTC) facilities (e.g., skilled nursing facilities) who wish to participate for the 2025-26 respiratory season. RespSafe is an immunization improvement and recognition program for facilities committed to improving their staff’s flu and COVID-19 vaccination coverage.

MDH endorses recommendations that include flu and COVID-19 vaccine for health care personnel (HCP). The American Academy of Family Physicians, the American College of Obstetricians and Gynecologists, and the Post-Acute and Long-Term Care Medical Association (PALTmed) recommend vaccinations for HCPs.

Organizations that choose to participate will be recognized based on flu vaccination coverage rates achieved, along with a strong encouragement of flu and COVID-19 vaccination with their staff and implementation of vaccine promotional activities. Questions about the program can be sent to health.re...@state.mn.us.


HPV vaccine confidence initiative featured in Minnesota Physician publication

From January through June, MDH and North Dakota State University Center for Immunization Research and Education (CIRE), launched a targeted initiative to strengthen provider communication around the human papillomavirus (HPV) vaccine. This initiative focused on delivering concise, peer-led, educational sessions aimed to equip health care providers with practical strategies to improve HPV vaccine conversations with patients and families. The article is featured in the September edition of Minnesota Physician, and highlights the goals, implementation, and challenges of this collaborative approach to enhancing vaccine confidence and uptake in clinical settings across Minnesota. Access the full article at Minnesota Physician: Closing the Gap: Strengthening HPV Vaccine Confidence.


Antibiotic-resistant pertussis

Over the past year Minnesota reported two cases of pertussis that were resistant to first line treatment antibiotics (ex. azithromycin, erythromycin, clarithromycin). One case had recently traveled to a country that has seen an increase in antibiotic resistance to pertussis. This increase has been seen in Europe, Asia, and South America. While most commercial reference labs are not able to assess antibiotic resistance, we are fortunate that the MDH Public Health Laboratory (PHL) performs Bordetella species cultures.

We are encouraging health care providers to consider sending specimens to MDH-PHL for PCR testing and subsequent culture when you are considering pertussis in someone who has had recent international travel. For more information on how to submit a specimen, visit Bordetella PCR and for information on requesting testing supplies visit VPD Test Kit Requests.

Minnesota is one of the first states in the U.S. to have reports of antibiotic resistance, in part because of our robust surveillance system and partnership with health care providers. For more information on pertussis and testing for pertussis refer to:

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