Paederia foetida Linn.
STINKVINEA climbing, herbaceous. hairy or smooth slender vine. The name derives from the distinct odor of carbon bisulphide when the leaves are crushed. Leaves are ovate to oblong-ovate, 6 to 10 cm long, 3.5 to 5 cm wide, pointed at the tip, rounded or slightly heart-shaped at the base. Flowers are stalkless, in axiallary, lax, peduncled inflorescences. Corolla is about 1 cm long, cylindrical, pale purple to white outside, deep purple and villous inside; limb is spreading with 5 undulate lobes. Fruit is rounded, about 5 mm diameter.
Distribution
In
thickets at low and medium altitudes.
Constituents and properties
Upon distillation, a volatile oil is obtained with the offensive odor of the fresh crushed leaves.
Two alkaloids are obtained: a- and b-Paederine.The leaves yield an indole.
Leaves are rich in carotene and vitamin C.Considered anodyne, emollient,
carminative, tonic, stomachic, vermifuge.Plant yields friedelan-3-1,
beta-sitosterol and epifriedelinol.Leaves yield iridoid glycosides, asperuloside,
paederoside and scandoside; sitosterol, stigmasterol, campesterol, ursolic
acid, palmitic acide and methyl mercaptan. The methyl mercaptan is responsible
for the foetid odor of the plant.
Uses
Folkloric
Used for rheumatism.
The leaves, boiled and mashed, applied to the abdomen for urinary retention.
Decoction of leaves also used for urinary retention and for urinary bladder
stones.
Decoction-soaked cloths applied to the forehead for fevers and taken internally
at the same time.
Bark decoction used as emetic.Decoction of leaves used for antirheumatic baths.
Pounded leaves applied to the abdomen for flatulence.
Decoction of roots for expelling gas.
Fruit used for toothaches and to blacken the teeth.
Decoction of whole plant used for abdominal pain, abscesses, arthritis.
In many Asia
traditional therapies, used for diarrhea and dysentery.
In Bangladesh,
used for diarrhea. Poultice of leaves used to relieve distention and flatulence
Roots and bark used as emetic, and in the treatment of piles and liver
inflmmation.
Fruit used for toothache.
In India
used for rheumatism and stiffness of the joints. Poultice of leaves applied to
abdomen to relieve distention and flatulence. Juice of the root is used for
piles, liver and spleen ailments.
Studies
• Antidiarrheal: Antidiarrhoeal
activity of the ethanol extract of Paederia foetida Linn. (Rubiaceae): Study
showed P. foetida has antidiarrheal activity by inhibiting intestinal motility
supporting its use in traditional medicine.
• Antiinflammatory: Investigation of the anti-inflammatory effects of
Paederia foetida: The study sought to find pharmacologic basis for the
ethnomedical use of the plant.
• Antispasmodic: Ethanolic extract
exhibited antispasmodic activity on isolated guinea-pig ileum.
• Anthelmintic: Juice of leaves showed potent anthelmintic effect
against bovine helminths–Strongyloides spp, Trichostrongylus and Haemonchus
spp.
• Antitussive Activity : Study showed the ethanolic extract of P foetida
had a cough suppressant effect, with decrease in cough intensity and frequency.
The effect was less than codeine but similar to non-narcotic dropropizine. The effect could be related to its demonstrated antiinflammatory activity.
• Antioxidant Activity : Study showed that P. foetida had high
antioxidant activity, with fresh samples having higher phenolic contents and
better antioxidant activity than the dried samples. It suggests PF could be a
significant source of natural antioxidant compounds.
• Hepatoprotective Activity : Study showed the methanol extract to have
moderate hepatoprotective activity.
• Anticancer Activity : Study showed the 50% ethanolic extract to have
anticancer activity against human nasopharyngeal epidermoid canrcinoma in
tissue culture.
Thank you Sheji ji for posting this plant...this is the first time iam seeing the flowers of this plant. . .ALso thanks to Murthy sir for providing the photograph...