If you're running Windows and you don't expect your list to get too large
(no more than a few thousand subscribers), you might consider using Arrow:
Arrow makes it very easy to create and manage both discussion lists and
announcement lists on your computer using a standard e-mail account
(POP3/SMTP). It uses "blind carbon copy" for sending messages so everyone's
address won't be revealed.
Arrow is free for one small list (50 subscribers or less). Registering it
for $50 removes the limitations.
-- Roger