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RCDI/eRCDI web-server for codon usage deoptimization
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Pere Puigbo
Apr 1, 2010, 10:33:35 AM4/1/10
to viro...@magpie.bio.indiana.edu
The RCDI server is a web-application that calculates the Relative Codon
Deoptimization Index (RCDI) and an expected value of the RCDI for a set of
query sequences by generating random sequences with similar G+C content and
amino acid composition to the input. The purpose of the server is to help in
the analysis of host-virus phylogenetic relationships or to infer the
potential host range of a virus and its replication strategy, as well as in
experimental virology to ease the step of gene design for heterologous
protein expression.
Deoptimization Index (RCDI) and an expected value of the RCDI for a set of
query sequences by generating random sequences with similar G+C content and
amino acid composition to the input. The purpose of the server is to help in
the analysis of host-virus phylogenetic relationships or to infer the
potential host range of a virus and its replication strategy, as well as in
experimental virology to ease the step of gene design for heterologous
protein expression.
RCDI/E-RCDI is and update of the server CAIcal (
http://genomes.urv.cat/CAIcal). This server is freely accessible at
http://genomes.urv.cat/CAIcal/RCDI.
For more details see Puigbo et al. (2010) BMC Reasearch Notes, 3:87.
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