Postdoctoral Position
Available
Iowa State University
Functional Genomics of Plant Disease Defense
A postdoctoral research position is available immediately in the Iowa
State University Center for Plant Responses to Enviromental Stresses
under the direction of Drs. Roger Wise and Steve Whitham. The
overall goals of the NSF-Plant Genome project "Functional Genomics
of Plant Disease Defense Pathways"
http://nsf.gov/awardsearch/showAward.do?AwardNumber=0500461 are to utilize functional genomics
tools and resources available to barley, rice, and the model dicot
Arabidopsis thaliana, to accelerate comparative analysis of
disease defense pathways important in agriculture.
Candidates will work with a team responsible for molecular, genetic,
and functional characterization of gene-specific sequences associated
with and required for R-gene mediated resistance responses
using barley powdery mildew as a model system. Approaches include
utilization of the 22K Affymetrix Barley1 GeneChip to characterize the
transcriptional networks regulated during powdery mildew induced
programmed cell death and subsequent high-throughput reverse genetic
systems in barley and Arabidopsis to functionally validate candidate
genes in resistance pathways of both monocot and dicot plants.
All of the above approaches will be facilitated by well-characterized,
high-resolution, recombinant mapping populations, accelerated
cell-death mutants, RNAi and TILLING silencing systems, BAC, cosmid,
and cDNA library resources.
Funding is available up to three years. Salary is commensurate with
experience. Ph.D. required in genetics, molecular biology, plant
physiology, plant pathology or related field. Experience in
bioinformatics/computational/statistical analysis, single-cell
transcript profiling, RNAi mediated gene silencing, cell biology,
and/or high-throughput gene mapping is desirable. Highly
motivated individuals should send curriculum vitae, research
interests, and reprints to the address below:
- Name, e-mail, address, phone, and fax no. of three references should
be included -
Dr. Roger Wise, USDA-ARS
Department of Plant Pathology
Iowa State University
Ames, IA, 50011-1020
rpw...@iastate.edu
Phone: 515-294-9756
Fax: 515-294-9420
http://wiselab.org/ ;
http://plexdb.org/
Recent Literature:
Shen, L, J Gong, RA Caldo, D Nettleton, D Cook, RP Wise, and JA
Dickerson. 2005. BarleyBase-an expression profiling database for plant
genomics. Nucleic Acids Research 33: D614-D618.
Caldo, RA, D Nettleton and RP Wise. 2004. Interaction-dependent gene
expression in Mla-specified response to barley powdery mildew.
Plant Cell. 16: 2514-2528.
Close, TJ, S Wanamaker, R Caldo, SM Turner, DA Ashlock, JA Dickerson,
RA Wing, GJ Muehlbauer, A Kleinhofs and RP Wise. 2004. A new resource
for cereal genomics: 22K barley GeneChip comes of age. Plant
Physiology 134: 960-968.
Halterman, D and RP Wise. 2004. A single amino acid substitution in
the sixth leucine-rich repeat of barley MLA6 and MLA13 alleviates
dependence on RAR1 for disease resistance signaling. Plant Journal 38:
215-226.
Iowa State University is an
Equal Opportunity/Affirmative Action Employer.