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Sheer Zebrafish available through MTA
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je...@silvaggi.com
Apr 10, 2013, 10:09:09 PM4/10/13
to bionet-organi...@moderators.isc.org, hen...@uwm.edu
Dear All,
I wanted to inform you of a very useful zebrafish model developed at the University of Wisconsin-Milwaukee by Dr. Henry Tomasiewicz. This triple homozygous mutant fish, known as sheer zebrafish, are characterized by their optically transparent quality throughout life. His laboratory has crossed mutants transparent (tra), albino (alb), and pfeffer (pfe) in which homozygous mutants are each defective in synthesis of different pigments (iridophores, melanin, and xanthophores respectively). Transparent zebrafish enable studies requiring the observation of cellular processes and interactions, and allow for manipulation of cells in adult fish. Sheer fish also allow for observation of all of the internal organs in the adult fish. These transparent fish are ideal for the study of fluorescent proteins, especially when studying the effects of environmental toxicants on neurodegenerative and other disease processes where optical clarity is at a premium.
The fish are available upon request by MTA. For further information please contact Dr. Jessica Silvaggi (jsil...@uwmfdn.org) or Dr. Henry Tomasiewicz (hen...@uwm.edu).
For more information please visit: http://uwmresearchfoundation.org/getdoc/8dbd80f6-008a-4ddc-b085-1f3e70a32a4e/(OTT1084)NCSHenryT.aspx .
Thanks,
Jessica Silvaggi
UWM Research Foundation
I wanted to inform you of a very useful zebrafish model developed at the University of Wisconsin-Milwaukee by Dr. Henry Tomasiewicz. This triple homozygous mutant fish, known as sheer zebrafish, are characterized by their optically transparent quality throughout life. His laboratory has crossed mutants transparent (tra), albino (alb), and pfeffer (pfe) in which homozygous mutants are each defective in synthesis of different pigments (iridophores, melanin, and xanthophores respectively). Transparent zebrafish enable studies requiring the observation of cellular processes and interactions, and allow for manipulation of cells in adult fish. Sheer fish also allow for observation of all of the internal organs in the adult fish. These transparent fish are ideal for the study of fluorescent proteins, especially when studying the effects of environmental toxicants on neurodegenerative and other disease processes where optical clarity is at a premium.
The fish are available upon request by MTA. For further information please contact Dr. Jessica Silvaggi (jsil...@uwmfdn.org) or Dr. Henry Tomasiewicz (hen...@uwm.edu).
For more information please visit: http://uwmresearchfoundation.org/getdoc/8dbd80f6-008a-4ddc-b085-1f3e70a32a4e/(OTT1084)NCSHenryT.aspx .
Thanks,
Jessica Silvaggi
UWM Research Foundation
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