Google Groups no longer supports new Usenet posts or subscriptions. Historical content remains viewable.
Dismiss

On Nervous-System<->Immune-System Interactions

0 views
Skip to first unread message

kpc

unread,
Apr 23, 2008, 3:45:39โ€ฏPM4/23/08
to
1. Don't reply, not because I don't want to
receive your thoughts, but because the last
'time' I read a post, other than one of my
own, my PC was completely-trashed, and
my telephone service 'disconnected'. [The
same thing has happened, repeatedly, in
the past -- I read discussions posted by
other folks, here in b.n, and my PC is
'trashed' by just having read such posts.
I'm Certain of this because I've restricted
my 'internet' use to exclusively reading and
posting here in b.n. =Yes=, it could be
that off-group folks have 'operated' in a
'technologically'-'sophistocated' way, in
which my PC is 'hacked' in preparation
for 'throwing-a-switch' "upon my next-
reading of a post that's been written by
someone other than" me -- I cannot dis-
tinguish between that possibility and the
possibility that it's been folks who post
here in b.n who've embedded destructive
executable instructions in what 'appear'
to be "regular messages". What I did
see, prior to my PC's being 'trashed' [for
about the 15th 'time'], was that my PC
was being 'hacked' in an incremental way.
I tried to counter such by remaining "con-
nected" for only as long as it took to post
whatever discussion I'd written, and then
immediately physically-disconnecting my
PC. But, as I noted in a msg I posted be-
fore my PC was 'trashed', I could see the
incremental-'hack' being constructed, de-
spite my fleeting "connections", in the same
post, also noting that I'd redoubled my ef-
forts to 'cram'-information-content in
anticipation of my PC's being 'trashed'.

[Well... go ahead and reply, if you want to,
but know, beforehand, that I cannot allow
myself to read anyone else's posts [so
=please= understand that, if I can't read
other folks' discussions, don't 'presume'
that I "don't want to". I =DO= want to
fully participate, in all possible ways, here
in b.n. My 'heart' is on-fire with such want-
ing-to-participate. But I cannot, not be-
cause I "don't want to", but be-cause some-
where in 'cyberspace', there're folks who
obviously want to 'prevent' me from doing
so.

So Please don't hold what 'they' do against
=me=.

I only want to =work=, and share the work
I do.]

I've 'fixed' the PC in order to post this one
msg.

I cannot convey my Sorrow -- there is so
much that remains to be communicated,
but my 'heart' is 'trashed', along with my PC.

What is the 'reason' that underpins these
repeated Savage-Attacks, which have been
going-on for 'decades' against my just
wanting to communicate the Science I've
done?

[The 'attacks' have been going-on for as long
as I've been online, trying to communicate
the Science I've done, in =every= online-'place'
I've ever tried to communicate the Science
I've done. It's a Savage-Violation of =every=
aspect of my Human-Being-ness. Vile, Sav-
age, and literally following me wherever I
go.]

So I resolved to work exclusively in b.n,
even though the Same-Stuff happens with
respect to my participation in b.n.

Posting discussions here in b.n is the =only=
'way' that's been 'open' to me. I've tried
every other way that I could think of, in-
cluding sending-out letters and papers,
traveling to visit folks in-person, telephone
calls [in which I usually just leave voice-
mail msgs.]

Doesn't anyone understand that work like
the work I've done [over the course of 46
'years'] cannot be communicated in little
snippets?

It can't.

I've rewritten all of Science.

That means that, no matter what aspect
of the work I've done I try to communicate,
I've =always= got to discuss stuff that will
be 'unfamiliar' to folks who work in trad-
itional perspectives.

I cannot, therefore, expect anyone to
"welcome" me -- be-cause I've =always=
got to tell folks that they're absent-under-
standing with respect to stuff in which, ac-
cording to the published literature of their
specializations, with which they are 'familiar',
they are "Experts".

So "Experts" always 'flip-me-off' as soon
as I =begin= to address the links that are
'unfamiliar' to them -- as soon as I begin
to discuss the stuff with respect to which
they remain absent-understanding.

"I'm used to it." [A. Lincoln]

I don't "take offense", at least not in any
way that's qualitatively-correlated to the
folks who routinely 'flip-me-off' [I admit,
it always 'hurts', because, the more it hap-
pens, the more one is 'pressed-in-the-vise',
hope, on one 'side', and foreknowledge
with respect to what 'blindly'-automated
TD E/I-minimization does on the other
'side', each 'time', the former being all
the more difficult to muster, and the lat-
ter being all the more 'foreboding' -- but
I'm not 'afraid' of the dynamics, inherent.
On the contrary, the more such happens
in my experience, the more-clearly I See
the Need to overcome the Savagery that's
inherent -- the more-clearly I See how
Savagely folks're Victimized by 'the beast',
"Abstract Ignorance" -- so, the more I be-
come Willingly-Obliged to "rescue" folks
from the Savagery. [I've been trying, all
along, to convey a 'sense' for the Tragedy
inherent. It's Fundamental-Essence is that
folks remain behaving in 'ways' that, through
their own behaviors, inflict-Savagery all-
around, which is flat-out an Inhuman 'way'
of 'existence' that's Sorrowfully-'hilarious',
because =everything= that =can= Enable
Trancendence 'above' such Savagery has
been innate 'within' human nervous systems
all along, but unrecognized, and, therefore,
unactualized. What I'm 'guilty' of is having
worked all of this through, and wanting to
give folks the understanding that enables
the Transcendence. 'high-crime'.]

So, to the folks who're doing the Savage-
'trashing' of this, the only way in which I
can communicate the work I've done,
=PLEASE STOP=.

'you' obviously don't know what 'you're
doing, because, if you did, you'd've realized,
by 'now', that the stuff 'you' 'presume' to be
so 'precious' pales-in-significance relative
to the stuff that remains to be communicated,
which 'you' should know, but obviously do
not know, because, if you did know it, 'you'
would also know that there's even-more-
precious stuff that, still-further, remains to
be communicated.

Instead, 'you' 'presume' that the stuff I've
already discussed is so "precious" that "it
is all that is needed", and 'you' 'decide' to
'terminate' my ability to communicate any-
thing else so 'you' can 'seek-profits' by
freely-using the stuff I've already commun-
icated, with respect to which, 'you' 'pre-
sume' that "it is necessary" to 'prevent' me
from communicating anything more, 'be-
cause', by doing so, 'you' will 'render me
disconnected from' Truth.

Which is Sorrowfully-'hilarious'.

All 'you' are doing is =Demonstrating=
'your' Sub-Human-Being-ness.

Be-cause the stuff that 'you' have 'gone-
ga-ga' over pales-in-significance relative
to the stuff 'you' would receive if 'you'
only allowed me to give it to 'you'.

"Of course", the 'problem', from 'your'
'perspective', is that, by working here
in b.n, I'm also giving everything I do
to =everyone= who reads in b.n.

=That= is the circumstance against
which 'your' Savagery is Directed.

'you' want to 'prevent' everyone else
from receiving the work I've done, and
want to share with =everyone=.

See how, and why, what 'you' do is
so-Extremely-Ugly?

=STOP= doing such.

All 'you' are actually 'doing' is Publicly-
Confessing 'your' Savagery.

[Or do you 'think' that there's a single
"character" that's ever posted in a news-
group that "is not" rigorously-coupled
to the machine upon which it was in-
stantiated?

If that's the case, please understand
that there is no such circumstance.

=Everything= that happens on the Inter-
net is uniguely-addressed. Everything
uniquely-traceable.

There exists no way to 'hide' in 'cyber-
space'.

Understand that I understand what
such means.]

Anyway, back to Nervous-system<->
Immune-System interaction.

If anyone read the discussions I posted
before my PC was 'trashed' [again ^ 15],
I was in the mids of beginning to reiter-
ate some stuff that I'd worked-through,
'years' prior, in my discussions of how
and why 'the genome' is, and can only
be, activated in rigorous accord with ex-
perience.

I could've rebuilt my PC, and been back
online, within a matter of 'hours', but, in-
stead, I decided to do some extended-
reading.

While doing so, I Verified the position I
was discussing before I got 'disconnected'.

I've Verified it in myriad ways, all of which
cross-Verify one another.

I want to discuss all of this stuff, and will
do so IFF the folks who're 'trashing' my
PC[s] 'back-off' and =THINK= instead
of 'cutting-themselves-off-at-the-feet'
[along with everybody else who reads
here in b.n], but I'll begin with brief =gen-
eral= comments with respect to "Autonom-
ic-Nervous-System" function.

Consider the Problem that's inherent in
"visceral"-control.

One "eats" stuff, for instance, not know-
ing whether or not the stuff contains tox-
ins.

There's a whole, relatively-independent
system, the "Enteric System", that, among
other things, is devoted to the Extreme-
Difficulty inherent in this one Problem.

Read about it, and you'll See that it's
functioning is governed centrally, with
the involvement of the hypothalamus,
brain stem, amygdala, cingulate cortex,
primary motor cortex, and prefrontal
cortex.

"Gut reactions" literally include Cog-
nitive dynamics.

I'm =NOT= saying that, "if the Enteric
System is disconnected from 'the' Cen-
tral Nervous System, all of the myriad
functions of the Enteric System will
cease".

I'm saying that, in such "vegatative"
disconnection, the functioning of the
Enteric System is left to "drift".

The absence of such "drift" when
central control is intact =greatly=
enhances the functioning of the Enteric
System -- by, for instance, enforcing
the 'rules' of "first-taste" aversion that
are routinely-observed in rats.

Understand?

What happens in the dynamics of first-
taste aversion [in which a rat will "take
a nibble" of an 'unfamiliar' substance,
and then aver from further eating of it]
is that the central processing achieves
relative TD E/I-minimization =with re-
spect to= the enteric-system dynamics
that occur as the "nibble" is "digested"
in the gut.

If there's an "adverse" reaction in the
gut, the rat will abstain from further
eating of the stuff.

"Learning" that governs Immune Sys-
tem function.

There are myriad analogous dynamics
that are mediated by Autonomic-Nerv-
ous-System function, all of them forms
of Cognition in which Immune-System
function is governed centrally.

The Sympathetic and Parasympathetic
Divisions of the Autonomic Nervous
System =LITERALLY= embody the
"inclined-planes" stuff that I discussed
a bit-prior to my PC's being 'trashed',
the one's 'state' of activation literally
counter-balancing the other's 'state' of
activation in a way that, centrally, liter-
ally defines their collective functioning
in a topologically-Directed way, in
which =everything= enters into the
high-'level' dynamics of TD E/I-min-
imization, which, via the hypothalamus,
uniquely-activates pituitary hormonal-
release, which modifies and tunes the
Immune Response [IR.]

Which is an Absolute Survival-Necessity.

Why?

Consider, for instance, what's inherent
in Sympathetic dominance.

"Alarm!" routinely followed by relative-
ly-forceful 'movement'.

What happens when forceful-'movement'
is manifested?

"Bruises", "cuts", "scrapes", "broken bones",
etc., "injury" and "pain".

So, although I didn't read of such in my
recent [still-ongoing] review-reading, it's
a Certainty that one thing that happens
in response to Sympathetic activation
is a centrally-mediated preparatory-re-
cruitment of Immune Response.

Why?

Be-cause, absent such preparation, it'd
be "too late" for the IR to have any chance
of being affective.

Understand?

Besides constricting the peripheral vas-
culature, Sympathetic activation also
"sounds the alarm" centrally, which cen-
tral TD E/I(up) is topologically-mapped,
which, when TD E/I-minimized, recruits
former Learning with respect to prior
"warning learning" [which has all been
discussed in AoK all along], which pri-
or Learning will determine behavioral-
reactivity, =INCLUDING= the unique
hormonal-release from hypothalamus,
which it's clear [at least to me :-] acts
to Direct Immune-System response in
a preparatory way that's tuned to, and
by, the net TD E/I.

Which is the stuff that I was discussing
before I got 'disconnected'.

It goes on and on like this. In my read-
ing, I took copious notes, Verifying
central control of Immune-System
function in myriad ways.

[Part of how and why this particular
'trashing' of my PC was so Hurtful
was that it occurred in the midst of
my =just-beginning= to Fix the pre-
vailing Error in which 'immune system'
function is 'presumed' to occur at a
'molecular-level'.

I was =just-beginning= to Fix this long-
standing Error, and I was 'disconnected'.

Try to understand how Great the Offense
actually was.

When one 'moves' to Fix long-standing
Error, one, =of course=, 'wades' right
into the middle of "doctrine", held to be
'true' by virtually everyone. So, in doing
such, one exposes one's self to extreme-
'criticism' -- the 'knee-jerk' stuff that
'always' accompanies instances of 'de-
parture'-from-'doctrine', simply be-cause,
such 'departures'-from-'doctrine' are de-
partures-from-that-which-is-'familiar' in
groupwise-coerced educational dynamics.

How and why being 'disconnected' when
I was =just-beginning= to Fix the long-
standing Error was so extremely-Offensive
was that it left me having only 'provoked'
the 'knee-jerk' =without= the means to
=guide= it's becoming TD E/I-minimized
across others' nervous systems.

Errors just =Need= to be Fixed, long-
standing, or not.

It's Egregiously-Offensive to 'throw-a-
bomb' into the midst of such endeavor-
on-behalf-of-generalized-understanding.

The Offense is virtually indistinguishable,
in its scope, from the Tragic events of
September 11, 2001, 'only' of =FAR=
more-Devastating Consequence.

I =Loathe= the Cowardice inherent in
the actions of those who'd 'thwart' com-
munication-of-understanding.

"Sympathetic Response".

See how, and why, it's all tied-together,
and what it physically is?]

Anyway... continuing my actual discus-
sion, that the long-standing Error has,
in fact, been long-standing, is 'pretty'-
'funny' because of stuff such as the
correlations that've been developed
with respect to "stress" and disease-
probabilities, and with respect to the
well-known dynamics of "inflamation"
[through which everything I discussed
prior to being 'disconnected', and the
stuff I'm discussing in this post, is rig-
orously-coupled to the dynamics of
"NL-P-Medicine", as I discussed them
in long-former posts here in b.n.]

=Here is what happens= via central
control of Immune-System function:

The molecular dynamics are literally
tuned by, and with respect to, TD E/I-
minimization.

With respect to all of the stuff that one
reads of, while one does reading in Im-
mune-System and Autonomic-Nervous-
System function, that says, "we don't
know how [this or that] happens" [of
which there's =a lot= of stuff], if folks
only look at the centrally-mediated
dynamics [instead of 'flipping-them-off'
because of the existence of long-stand-
ing doctrine], folks'll find that it's the
central-tuning, via TD E/I-minimization,
that govern 'all' such stuff.

Take it as a Prediction.

[I've already Verified that it's so. The
Verification is already written-into my
notes.

I'm still 'two'-'pissed-off' -- too-Symp-
athetically-activated [:-] -- to get out my
notes to discuss it [partly, be-cause the
Verification was such a 'forced-march'
that I'm 'exhausted', partly be-cause I
want to See if I'll be allowed to post
this discussion before discussing the
"Deep"-Verification, and partly be-
cause my Spirit is still Ravaged by the
'disconnection' happening with respect
to work =here in b.n=, a 'place' that
I Love.]

What to look for, in the Testing of the
Prediction above, is stuff like correla-
tions between pituitary-release concen-
trations and IR.

The pituitary-conenntrations are Prob-
ably an ordered-signal that Directs IR.

["Of course"] to See such, one has to
understand the dynamics of "refrac-
tion" amongst "SSW<->UES harmon-
ics", and I don't know if I've discussed
the latter stuff sufficiently, 'yet', to en-
able others to See the "refractive"-tun-
ing dynamics. If that's the case, then I
=wish= someone would allow me to
come to them, to show them how [and
why] to do such calcs, in-person.

The going-forward of =all= of Pharm-
acology =Depends= upon folks under-
standing the stuff I've briefly discussed
in this msg.

Be-cause, the stuff I've discussed above
forms the 'heart' of the dynamics of
"functional multiplexing" as it's been dis-
cussed in AoK, Ap9, all along.

The is =Zero= Possibility of achieving
any actually-functional Pharmacology
without, first, Resolving the Functional-
Multiplexing Problem.

What I'm saying, here, is that the route
to the Resolution of the Functional-
Multiplexing Problem goes straight-
through the stuff I've discussed above
in this post.

If I'm allowed to, I'll discuss it all thor-
oughly.

I've already worked-the-Problem
through.

Almost fell-off-my-chair because
"Toxoplasma Gondii" was "the Key" :-]

[Just like I'd proposed in my discus-
sion of t. Gondii last 'year'.]

With-Love, if from the 'depths'-of-
my-Sorrow,

k. p. collins


kpc

unread,
Apr 24, 2008, 8:19:17โ€ฏAM4/24/08
to
"kpc" <HavaG...@sufficient.org> wrote in message news:DlMPj.6818$i45.2344@trndny01...

| 1. Don't reply, not because I don't want to
| receive your thoughts, but because the last
| 'time' I read a post, other than one of my
| own, my PC was completely-trashed, and

| my telephone service 'disconnected'. [...]

I did an experiment that disclosed that my
virus software bypasses my modem hard-
ware firewall.

=That= is Probably how the 'hack' was im-
plemented [because the virus software
needs periodic database-updates, which
were the only web-access I was allowing
my PC to do.]

If this's the way that my PC was 'hacked',
it means that the folks who're doing the
'hacking' are 'big-gun'-'technologists',
and there's no hope that I'll be able to
circumvent their doing more of the same.

So I'm Probably just going to let them do
their Jackass-stuff -- be-cause, after suc-
cessfully(?) posting the post linked-to
above, here in b.n, I realized that it'd been
the Joy of my being able to participate
here in b.n that'd been my Sustinence --
the "thing" that'd enabled me to endure
the work.

It's 'funny' -- having to impose "not-read-
ing" of the discussions other folks post
here in b.n -- amongst whom are folks who
I Value as Friends -- "sucked the wind out
of my sails". There's nothing left from which
I can gain the Sustinence that enabled me
to endure what is, otherwise, a Hard ex-
istence.

So I'm going to discuss one more thing,
and, then, 'withdraw' to recover, as best
I can, from the Loos of my Friends here
in b.n.

| I've 'fixed' the PC in order to post this one
| msg.

| [...]

And this one :-]

| I've rewritten all of Science.

I'm not "kidding". I'll gladly Demonstrate,
in-person. I've been trying to not make-a-
big-deal out of such, because I didn't want
it to become "the main thing".

The main thing is the information-content,
and the need to Fix what was Broken in
Science.

But I'm not "kidding".

I've rewritten all of Science.

| That means that, no matter what aspect
| of the work I've done I try to communicate,
| I've =always= got to discuss stuff that will
| be 'unfamiliar' to folks who work in trad-
| itional perspectives.
|
| I cannot, therefore, expect anyone to
| "welcome" me -- be-cause I've =always=
| got to tell folks that they're absent-under-
| standing with respect to stuff in which, ac-
| cording to the published literature of their
| specializations, with which they are 'familiar',
| they are "Experts".
|
| So "Experts" always 'flip-me-off' as soon
| as I =begin= to address the links that are
| 'unfamiliar' to them -- as soon as I begin
| to discuss the stuff with respect to which
| they remain absent-understanding.
|
| "I'm used to it." [A. Lincoln]

| [...]

But I'm still under =Terrible= Obligation
with respect to the Need to Communicate
stuff.

I'll never get "used to" that.

| So, to the folks who're doing the Savage-
| 'trashing' of this, the only way in which I
| can communicate the work I've done,

| [...]

You've 'won'.

'now' what will 'you' do?

| 'you' want to 'prevent' everyone else
| from receiving the work I've done, and
| want to share with =everyone=.

| [...]

But all 'you' have 'succeeded' in 'accomp-
lishing' is that 'you' will remain absent-
understanding.

| Anyway, back to Nervous-system<->
| Immune-System interaction.

| Consider the Problem that's inherent in

| System -- by, for instance, enforcing [stuff like] <- edited


| the 'rules' of "first-taste" aversion that
| are routinely-observed in rats.

| [...]

| There are myriad analogous dynamics
| that are mediated by Autonomic-Nerv-
| ous-System function, all of them forms
| of Cognition in which Immune-System
| function is governed centrally.
|
| The Sympathetic and Parasympathetic
| Divisions of the Autonomic Nervous
| System =LITERALLY= embody the
| "inclined-planes" stuff that I discussed
| a bit-prior to my PC's being 'trashed',
| the one's 'state' of activation literally
| counter-balancing the other's 'state' of
| activation in a way that, centrally, liter-
| ally defines their collective functioning
| in a topologically-Directed way, in
| which =everything= enters into the
| high-'level' dynamics of TD E/I-min-
| imization, which, via the hypothalamus,
| uniquely-activates pituitary hormonal-
| release, which modifies and tunes the
| Immune Response [IR.]

| [...]
|
| Besides [doing myriad things like] <- edited


| constricting the peripheral vas-
| culature, Sympathetic activation also
| "sounds the alarm" centrally, which cen-
| tral TD E/I(up) is topologically-mapped,
| which, when TD E/I-minimized, recruits
| former Learning with respect to prior
| "warning learning" [which has all been
| discussed in AoK all along], which pri-
| or Learning will determine behavioral-
| reactivity, =INCLUDING= the unique
| hormonal-release from hypothalamus,
| which it's clear [at least to me :-] acts
| to Direct Immune-System response in
| a preparatory way that's tuned to, and
| by, the net TD E/I.
|
| Which is the stuff that I was discussing
| before I got 'disconnected'.

| [...]

And which is what I want to briefly dis-
cuss, further, in this "last"(?) discussion
I'll post here in b.n.

| [Part of how and why this particular
| 'trashing' of my PC was so Hurtful
| was that it occurred in the midst of
| my =just-beginning= to Fix the pre-
| vailing Error in which 'immune system'
| function is 'presumed' to occur at a
| 'molecular-level'.
|
| I was =just-beginning= to Fix this long-
| standing Error, and I was 'disconnected'.

| [...]

=OF COURSE= the action of the Immune
system occurs at the molecular-'level'.

But "bodies" require, Absolutely, global-
integration of =all= functionality -- else
"bits and pieces" function at cross-pur-
poses, which is literally a disease dynamic
[be-cause, to the degree of it, cross-purpose
'functionality' is =DISORDERED= 'func-
tionality', which is what "disease" physic-
ally is.]

The global-integration can only happen
in nervous systems, be-cause nervous
systems are the only systems that have
global access to 'the' body.

Immune effectors =have to= act locally
be-cause their disease-agent targets ex-
ist locally.

But there are =myriad= things that can
only be Determined and Governed in
a globally-integrated way, like, for in-
stance, the matching of Immune-System
"actions" with available nutrient-concen-
trations -- the IR cannot use stuff that's
not physically-extant within 'the' body,
yet, the IR =MUST= be instantiated in
any way that it can be instantiated.

Stuff like the matching of IR governance
with available-nutrients can only occur
centrally -- be-cause organ-activations
must be configured =across 'the' whole
body= if various organs' molecular out-
puts are to be tuned with respect to a-
vailable-nutrient compositions.

In the prevailing conceptualization of
the IR, such inter-organ "cross-talk" is
'presumed' to occur molecularly, via
circulatory-communication, and I'm =NOT=
'discounting' such. It definitely occurs.

It's just that =much-more= than it occurs
in myriad ways that are mediated and
governed centrally.

One cannot miss Seeing the central dyn-
amics if only one keeps one's mind open
to them as one reads in the literature.

Why keep one's mind open to such, when
'doctrine' 'discounts' such?

Because of the =vast=, greatly-enhanced,
capabilities that are flat-out obviously in-
herent in central control and governance.

Capabilities that are so functional, that
it's Certain that Evolutionary Dynamics
would not miss the opportunity to instan-
tiate them [which is in my own understand-
ing of Evolutionary Dynamics, that I've
not discussed very much, but use routine-
ly, routinely with substantial results, which,
I understand, is open to question from
standard perspectives, but which I'll glad-
ly Demonstrate, to anyone's Satisfaction,
in-person. My view on Evolutionary Dyn-
amics is, basically, that, if doing "it" en-
hances an organism's ability to 'climb'
WDB2T, Evolutionary Dynamics do "it".
The result of such is that what've been
'presumed' to be "compartmentalized'
functionalities, are Seen to, instead, be
globally-integrated, yet distributed, func-
tionalities. What initialized the develop-
ment of this view of Evolutionary Dyn-
amics was, BTW, my study of the work
done by Karl Lashley in nervous-system
"memory" dynamics, encapsulated in
his concepts of "mass action" and "eqi-
potentiallity". Folks who work in neuro-
science [and in =any= biological Science,
for that matter], would do-well if they'd
study the work of Lashley, too [and not
'discount' it], be-cause, doing so Teach-
es one how, and why, to See the sorts of
globally-integrated, yet distributed, func-
tionalities that I pointed-out, above. Bas-
ically, what it all means is that the func-
tioning of, say, groups of neurons in a
"nucleus" are evolved with respect to
vastly more than stuff such as their ob-
vious physical-interconnectedness --
that the functional-properties of any
neuron are evolved with respect to the
functioning of stuff that's widely-distrib-
uted in 'the' body -- in ways that're anal-
ogous to Lashely's principles of "mass
action" and "equipotentiality" [=DON'T=
'knee-jerk', in accord with what's 'fashion-
able' with respect to 'getting papers pub-
lished. Lashely's work 'is an easy target'
'within' the behavioral dynamics of such
'fashion'. Instead, use your own good 'ol
noggin labs to =THINK=. It's Preposterous
to 'presume' that Evolutionary Dynamics
"would not take advantage of the Oppor-
tunity" to enhance organisms' abilities to
'climb' WDB2T 'just because' it's 'presumed'
that "this organ does this or that".

Understand?

Evolutionary Dynamics do =whatever=
enhances organisms' capacities for 'climb'-
ing WDB2T.

'the' =whole= body is this way.

Stop not-Seeing such.

Researchers are looking at it every 'day',
but not Seeing it [which happens, in the
main, be-cause there's inordinate empha-
sis on "specialization", which 'emphasis'
leaves folks absent-understanding with
respect to stuff that's not 'emphasized' in
their area of "specialization". [Forgive me,
Please, this stuff is more of the stuff inher-
ent in my oft-reiterated Lament with re-
spect to the fact that folks in Neuroscience
routinely 'skip' Learning the Neuroanatomy,
routinely, in favor of 'catching-band-wagon-
itus' with respect to 'molecular' consider-
ations -- because, that's where the funding
is.

What good is 'being funded', if 'being fund-
ed' renders one 'blind' to what's =in= the
stuff that's, right there, on one's lab-bench
every 'day'?

I =did= ask your Forgiveness.

It's just fallen to me to 'have to' say stuff
like the above sidebar on Evolutionary
Dynamics. I 'hold my nose', and do it --
in this discussion, in particular, be-cause
it's Probably the "last" discussion I'll post
online.

'the' body is =Globally-Integrated=.]

| Anyway... [...]

| =Here is what happens= via central
| control of Immune-System function:
|
| The molecular dynamics are literally
| tuned by, and with respect to, TD E/I-
| minimization.
|
| With respect to all of the stuff that one
| reads of, while one does reading in Im-
| mune-System and Autonomic-Nervous-
| System function, that says, "we don't
| know how [this or that] happens" [of
| which there's =a lot= of stuff], if folks
| only look at the centrally-mediated
| dynamics [instead of 'flipping-them-off'
| because of the existence of long-stand-
| ing doctrine], folks'll find that it's the
| central-tuning, via TD E/I-minimization,
| that govern 'all' such stuff.
|
| Take it as a Prediction.
|
| [I've already Verified that it's so. The
| Verification is already written-into my
| notes.

| [...]

| What to look for, in the Testing of the
| Prediction above, is stuff like correla-
| tions between pituitary-release concen-
| trations and IR.
|
| The pituitary-conenntrations are Prob-
| ably an ordered-signal that Directs IR.

| [...]

To =begin= to study such is relatively-
easy.

Use animal subjects to develop dynamic-
molecular-monitoring of blood-flow-exit-
ing-the-pituitary capabilities [which, "of
course", will have to occur at distances
from the pituitary -- there's worth in doing
such, be-cause such dynamic-monitoring
capabilities will, in the future, become the
"Gold-Standard" of Medical Diagnoses
[a Prediction.]]

[I'm =not=, BTW, asserting that the pituit-
ary is the primary, or only, outlet for cen-
trally-governed molecular-configuration
dynamics. It's just the most-obvious, so
I'm using it in this discussion.]

The Problem ["of course"] consists of
using such dynamics-monitoring methods
to gain-understanding with respect to how
and why pituitary [etc. sites] outputs are
"coded" with respect to the actualities of
circulatory dynamics.

The first thing I'd look for would be a "pulsed-
release" that's has "stress"-correlated dynam-
ic properties.

This, be-cause, in periods of "stress", sympa-
thetic activation increases the rate of blood-
flow [etc., myriad analogous, all 'normally'
globally-integrated dynamics.]

The gist being that any "pulsed"-molecular
"coding" would be:

1. matched to blood-flow rate, which would
make it relatively-easy to detect using mol-
ecular-constituent detectors whose outputs
are coupled to blood-flow-rate monitors [it
will Probably be necessary to develop a
"blod-flow-spreading" 'field'-detector, so
that individual molecular detectors can be
distributed-upon it, and a thin layer of
blood passed-over it -- in order to facili-
tate optimal molecular-detection. [Don't
'whine' about the "technical difficulty".
Just do it. It's the future of Medical Dia-
gnosis, after all :-]

2. The idea is that a "pulsed" molecular
dynamic can, very-easily, encode and com-
municate "instructions" to Immune Sys-
tem functional-dynamics, be-cause blood-
flow-rate is, in fact, a globally-determined
thing during 'the' "stress"-response --
which would, on fine-tuned-average, "ping"
Immune-System constituents in a way that
provides a 'sequential'-tuning signal.

Understand?

It's exactly-analogous to any other seq-
uentially-encoded signalling -- like the
"Morse Code", but in a fluid-medium
[but, also, having 3D qualities that'll be
correlated to vessel-size, type, organ-
vessel-ramification, etc., etc., etc.]

3. Since 2., is True, if it occurs [I'll be fall-
off-my-chair-Surprised if it 'does not'], mol-
ecular-pulse-encoding can be easily detected
because, as blood-flow-rate alters, molecular-
release-"pulses" will have to alter to "keep-
pace" with the blood-flow-rate.

4. The not-so-easy part stems from the fact
that, when blood-flow-rate alters, 'level' of
"stress" is also altering, so the outputs of
the pituitary [etc., "glands"] will've altered
at some 'time' prior. The detection-apparatus
has to be designed to capture such non-sim-
ultaneous cross-correlateions -- which is
easy to do via post-trial computer-analysis
IFF the necessary data are, in fact, detected
and stored. [Don't 'presume' "what data is
important". Work to capture as many differ-
entials is is Possible.]

I'd have to Study the state of the art in mol-
ecular-detector design [my 'understanding'
of molecular-detection in the Human Genome
Projects leads me to expect that what already
exists is a step in a direction that's useful with
respect to this stuff I'm discussing, but the
stuff I'm discussing has to work-faster] before
I'd be ready to do so, but I'll gladly show folks
how, and why, to construct such machines,
including Teaching folks how, and why, to
do the SSW<->UES harmonics "refraction"
calcs, which are straight-forward, if 'different'
from what folks already are 'familiar' with.

With respect to the latter, there was a blurb
with respect to a local TV-News Report 'yes-
terday' [CBS, Channel 3 in Hartford, CT],
which repeated this 'day'. Although I waited
for it, I didn't catch the Report be-cause the
signal-strength faded at my "rabbit-ear" TV
antenna :-[, but the "blurb" was sufficient.

What it showed was video of a Surfer who
was Surfing a eddy-"wave" in the Connect-
icut River.

The guy was literally "standing-in-place"
by adjusting the angle-of-incidence of his
surfboard with respect to the dynamically-
varying refractive-index of the "wave".

I enjoyed watching it very-much -- because
it's information-content was so Enormous.

Anyway, the gist of the above "pulsed-
coding" stuff is closely-analogous to the
Surfer's interaction with the river-"wave".

"Pulsed" molecular dynamics "pulse" the
refractive-index of the circulating-blood,
so all Immune-System dynamics have to do
to "read the code", and act-upon its govern-
ing-signal, is to, just like the Surfer, alter
angles-of-incidence with respect to the
"pulse"-wave's refractive-index -- "stand-
ing-in-place", but dynamically-altering as
the "pulse"-coded instructions govern.

The idea being that Immune-System func-
tion is dynamically tuned and governed,
via central-TD E/I-minimization dynamics,
in thisway, and Probably other ways that
are analogous to it.

This sort of signalling-dynamic is =very=
easy to functionally-multiplex be-cause
it can be 'crammed'-with-data, but, since
the "reading" of signals is done by spec-
ific molecular dynamics, specific molecu-
lar dynamics can easily extract the "data"
that are pertinent to their own function-
ing.

[I'm actually Certain, BTW, that the stuff
I've discussed above does occur.

One can See all of it in just looking at a
"ribbon"-diagram of a human "IgG" mol-
ecule.

I'm already Certain that it is the future of
all Medical Diagnoses with respect to
disease processes and agents. [=Of course=
other such advances will supercede it,
but it's a Pretty-Good "stepping-stone"
to those. It will vastly-improve all of
Medical Science, and all those other such
advances? They will all =Necessarily= Pre-
serve the basic stuff I've shared with folks,
above.]

"Anyway"...

I =Love= you all so much, my Friends
here in b.n.

I Hope to heal-my-wounds, sufficiently,
to rejoin you, one 'day', but, just 'now',
I cannot See that I'll ever be Free to do
so, and, meanwhile, "the wind is out of
my sails". You folks have been 'interpers-
onal'-"everything".

'the beast' is 'angry' with me,

wants to 'silence' 'me',

be-cause, I've 'moved',

With-Love,

k. p. collins


N

unread,
May 4, 2008, 8:06:07โ€ฏPM5/4/08
to
On 24 Apr, 13:19, "kpc" <HavaGood...@sufficient.org> wrote:
> "kpc" <HavaGood...@sufficient.org> wrote in messagenews:DlMPj.6818$i45.2344@trndny01...
> functioning of stuff ...
>
> read more ยป

work hard big guy, rewards are often granted, hopefully the right
reproduce ;) the one they always put outta your reach on all
and every occassion

0 new messages