Linkage Coefficient r = D/[p(1-p)q(1-q)]1/2
= -0.016/(0.9*0.1*0.33*0.97)1/2
= -0.046
#param Ln(L) Chi-square
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H0: No Association 2 -1074.53 0.00
H1: Allelic Associations Allowed 3 -1072.23 4.59
1. How do we determine significant linkage values, is there a reference
or range available for interpretation?
2. What is the meaning of a negative LD and linkage coefficient?
3. What is the relationship between them?
4. What does the linkage coefficient tell us? how is the value
interpreted?
THANX.