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Postdoc in Biomaterials-based Approach for Stem Cells Differentiation

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Ema Shollenberger

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Feb 7, 2019, 1:22:19 PM2/7/19
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Are you interested in the interplay between regenerative medicine and materials science?

A postdoctoral position is available at the Biomimetics, Biocarriers and Bioimplants group (The 3Bs) headed by Assoc. Prof. Leticia Hosta-Rigau, DTU Health Tech, Technical University of Denmark, Kgs. Lyngby, Denmark.

The 3Bs is a highly interdisciplinary and positive group with open-minded and supportive members. The 3Bs research lies on the interface of materials science together with molecular and cell biology. The research focus areas of the group are drug delivery, tissue engineering and cell mimicry.

The 3Bs are well embedded into the Biopharma division, where multiple young research groups work closely together to create a motivating environment.

Within this announced position, we will develop a biomaterials-based approach to direct the differentiation of stem cells (ASCs and iPSCs) towards various/different tissue-specific cells.

The position is available as soon as possible.

Stem cells are able to differentiate into any cell type of the human body and, as such, hold tremendous potential in tissue engineering, cell replacement therapy and drug screening. However, current differentiation procedures mainly rely on the use of growth factors and/or feeder cells, resulting in heterogeneous cell types, lack of repeatability, immune rejection and contamination.



Since it is now widely accepted that biophysical cues (i.e., topography or matrix elasticity) play an equally important role in governing cell's fate, engineered biomaterials have emerged as a powerful tool to direct stem cell's fate avoiding (or at least minimizing) the use of the less-safe biochemical factors.

The successful candidate will work in a highly interdisciplinary project in the interface of materials science together with molecular and stem cell biology.

For instructions on how to apply, please refer to: http://bit.ly/2GtGysh
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