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Animals and Blood Types

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Stock up and save. Limit one.

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Dec 29, 1995, 3:00:00 AM12/29/95
to
ok. so I've looked in "Fundamental Immunology" and "Cellular and
Molecular Immunology" for the answer to this one and cant find it, so
here goes:

a colleague of mine said that he heard a story on the news involving a
local veterinary hospital and a "donor cat", which was well cared for
and served to "donate" blood for surgeries. he asked whether animals
have blood types (sounds like a loaded question to me, so be patient
in your replies...). a local vet told him that such procedures are
rarely done, but he never really answered the question.

sorry if this post doesn't seem germane to this group, but it's the
closest I can come within the "bionet" hierarchy. pointers to
literature references or books would be appreciated.

thanks
pat martin


Ian A. York

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Dec 29, 1995, 3:00:00 AM12/29/95
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In article <pkmartinD...@netcom.com>,

Stock up and save. Limit one. <pkma...@netcom.com> wrote:
>and served to "donate" blood for surgeries. he asked whether animals
>have blood types (sounds like a loaded question to me, so be patient

Animals do have blood groups. In some cases (eg cattle, as I recall) the
groups are much more complex than in humans. In others (as in cats) most
are of one type (>90% type A in cats). The risk of a single transfusion
is low, as the odds of a pre-existing response to the transfused blood is
slight. Subsequent transfusions, of course, make the risk higher.
I think there are specialized labs for typing animal blood. In most
cases, of course, this isn't done (as the transfusion is an emergency).
I think you can do quick-and-dirty in-house assays to check for
reactions. I suspect that many clinics don't do even this, and play the
odds when necessary; but I'm not an expert by any means.

Ian


--
Ian York (iay...@panix.com)
Dana-Farber Cancer Institute, 44 Binney St., Boston MA 02115
Phone (617)-632-3921 Fax (617)-632-2627

Jeffrey Frelinger

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Dec 29, 1995, 3:00:00 AM12/29/95
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Animals have blood types, but not all have natural blood group specific
antibodies. There is an old hughe literature on this, some of whic I once
knew, but have forgotten. There is/was a journal Animal blood groups and
biochemical genetics. See if you can find it.
BTW famouys cattle blood groups story is that tolerance was discovered by
blood typing cattle. True story done by my old PhD mentor Ray Owen.
Jeff Frelinger

At 06:39 PM 12/29/95 +0000, Stock up and save. Limit one. wrote:
>ok. so I've looked in "Fundamental Immunology" and "Cellular and
>Molecular Immunology" for the answer to this one and cant find it, so
>here goes:
>
>a colleague of mine said that he heard a story on the news involving a
>local veterinary hospital and a "donor cat", which was well cared for

>and served to "donate" blood for surgeries. he asked whether animals
>have blood types (sounds like a loaded question to me, so be patient

Paula Sanch

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Jan 2, 1996, 3:00:00 AM1/2/96
to
pkma...@netcom.com ("Stock up and save. Limit one.") wrote:
>... pointers to

>literature references or books would be appreciated.
>
Without doubt, there are other experts, but the only one I've ever met
was at the Michigan State vet school. He did extensive research on
bovine blood groups, but consulted on other species as well. Now if
I could just remember his last name . . . (blush) He headed a large
project typing bovine bloods in the 1970s.

If you started looking for antigen groups literature in the 1970s to
early 80s in the veterinary medical journals, you'd find information,
I'm quite sure.


Jeffrey Frelinger

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Jan 2, 1996, 3:00:00 AM1/2/96
to
I don't know the MSU guy by Clyde Stormont did a ton of cattle blood group
stuff at UC Davis.
Jeff Frelinger

Paula Sanch

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Jan 4, 1996, 3:00:00 AM1/4/96
to
Paula Sanch <Paula...@emich.edu> wrote:
> ... bovine blood groups, but consulted on other species as well. Now if

>I could just remember his last name . . . (blush) He headed a large
>project typing bovine bloods in the 1970s.
>
(blush *really* hard, but you'll all understand why)
His name is Robert Bull.


Dr. Mike Clark

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Jan 5, 1996, 3:00:00 AM1/5/96
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In article <jcherwon.9...@dres.dnd.ca>, John Cherwonogrodzky
<mailto:jche...@dres.dnd.ca> wrote:
> There has been an interesting discussion started on animals and their
> blood groups. I'm curious, are there any related to human blood groups?

There are some problems analogous to human disorders which depend upon
animal blood groups. For example horses and I think pigs can suffer from
haemolytic disease of the newborn (HDN) following aquisition of maternal
immunoglobulin specific for paternal blood group antigens.

Mike Clark, mr...@cam.ac.uk http://www.path.cam.ac.uk/~mrc7/
--
o/ \\ // || ,_ o Dr. M.R. Clark, Division of Immunology
<\__,\\ // __o || / /\, Cambridge University, Dept. Pathology
"> || _`\<,_ // \\ \> | Tennis Court Rd., Cambridge CB2 1QP
` || (_)/ (_) // \\ \_ Tel. 01223 333705 Fax. 01223 333875


John Cherwonogrodzky

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Jan 5, 1996, 3:00:00 AM1/5/96
to
Dear Colleagues:

There has been an interesting discussion started on animals and their
blood groups. I'm curious, are there any related to human blood groups? Do the
animal blood groups have their own nomenclature? I would imagine that some
animals do have human blood groups. As a kid I remember reading about how
Harvey in merry old England did the first blood transfusions of sheep to
humans. Sometimes it worked (matched blood groups), often it didn't. Take
care...John

JRDVMDIVER

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Jan 5, 1996, 3:00:00 AM1/5/96
to
Hello
I am an equine veterinarian, most of the following information comes from
Large Animal Internal Medicine, ed; Brad Smith, 1990:

Animal Blood Groups
Equine A,C,D,K,P,Q,U
Bovine A,B,C,F,J*,L,M,R',S,T,Z
Ovine A,B,C,D,M,R,*X
Caprine A,B,C,M,J*

Blood Group Factors of the Horse (7 groups / 32 factors)
(Q and A are most clinically relevant factors, Neonatal Isoerythrolysis)
A Aa,Ab,Ac,Ad,Ae,Af,Ag
C Ca
D Da,Db,Dc,De,Df,Dg,Dh,Di,Dk,Dl,Dn,Do,Dp
K Ka
P Pa,Pb,Pc,Pd
Q Qa,Qb,Qc
U Ua

Blood Group Factors/Antigens of the Bovine (11 groups / >120 factors)
B and J most clinically relevant groups

Blood Group Factors/Antigens of the Ovine (7 groups / > 52+ factors)
B, R, M-L most clinically important groups

Blood Groups of K9's
A is most clinically important group

We do major and minor crossmatches in our labs, keep Q and A negative
blood donor horses where we can, and use unrelated geldings if no other
donor is available. We have labs around North America that do blood
typing for identifying potential donors, some breed registries require
blood typing for registration, and for parentage testing. A single plasma
or whole blood transfusion in most cases is not a problem, the risks
increase with each subsequent transfusion even from known Q and A negative
donors. For more information see a veterinary immunology text, internal
medicine text, etc...

Good Luck IMHO O-) Dr JR
email JRDVM...@aol.com
Julie A. Robinson DVM, MVSc, MS, DABVP (Equine)
All Standard Disclaimers Apply...

JRDVMDIVER

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Jan 6, 1996, 3:00:00 AM1/6/96
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In article <ant051651868h9e%@mrc7acorn1.path.cam.ac.uk>, "Dr. Mike Clark"
<mr...@cam.ac.uk> writes:

>There are some problems analogous to human disorders which depend upon
>animal blood groups. For example horses and I think pigs can suffer from
>haemolytic disease of the newborn (HDN) following aquisition of maternal
>immunoglobulin specific for paternal blood group antigens.
>
>

Neonatal foals can develop Neonatal Isoerythrolysis, similar to R factor
incompatablities in humans. The Q and A groups are the biggest problem.
The foal inherits the sire's blood type, the mare has antiRBC-antibody in
the colostrum, the foal ingests and absorbs the colostrum and develops NI.
We also have some evidence of Neonatal AlloImmune Thrombocytopenia in
mules foals.

un...@teleport.com

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Jan 6, 1996, 3:00:00 AM1/6/96
to
> From: pkma...@netcom.com ("Stock up and save. Limit one.")
> Subject: Animals and Blood Types
> Date: Fri, 29 Dec 1995 18:39:49 GMT

>
> ok. so I've looked in "Fundamental Immunology" and "Cellular and
> Molecular Immunology" for the answer to this one and cant find it, so
> here goes:
>
> a colleague of mine said that he heard a story on the news involving a
> lcal veterinary hospital and a "donor cat", which was well cared for

> and served to "donate" blood for surgeries. he asked whether animals
> have blood types (sounds like a loaded question to me, so be patient
> in your replies...). a local vet told him that such procedures are
> rarely done, but he never really answered the question.

In addition to the other posts on this subject: my understanding is that
dogs, in particular, have 26 blood types. There is at least one dog blood
type that is general--kind of an umbrella blood type. This blood type can
be transfused into dogs of other blood types without causing reactions.
Some vets do keep a donor dog of this blood type on the premises, usually
when the animal has been abandoned by other owners. Sometimes, the
vet discovers a client's pet (must be a large dog, btw) with that particular
blood type. In this case, if the dog is large, such as an Akita, the vet may
ask the client to allow his/her dog to become a blood donor for other,
critical patients. A small/medium dog with the general blood type is not
a suitable donor because, of course, the amount of blood required for
most surgeries is beyond a small animal's capacity to donate and sustain
its own life/health.

Hope this helps.

- Tara K. Harper
un...@teleport.com

/ Even a thought /
/ Even a possibility can shatter us and transform us /
/ - Nietzsche /


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