Molecular Modelling - Experienced Scientist
Research & Development
Denmark - Måløv
The Department of Haemophilia Biochemistry is seeking an experienced scientist for structure-guided protein optimization and designAbout the DepartmentHaemophilia Biochemistry is an integral part of the Novo Nordisk haemophilia research area in Global Research located in Måløv. We are a diverse department with 22 enthusiastic scientists, research assistants, and students who all support the haemophilia research portfolio through innovation and structure-guided design and development of novel protein-based therapies. The department has a solid base of expertise in haemostasis biology, mode of action studies, protein chemistry, enzyme assays, protein-ligand interaction studies, and molecular modelling.The Job
This is a dynamic and challenging position in an innovative discovery department with many cross-functional activities in project teams and focus groups. Ambitious scientific goals will require collaboration with highly specialized colleagues. Your main focus will be structure-guided design and development of novel protein therapeutic candidates as well as proteins with improved biological, formulation, and pharmacological properties. Your responsibilities will include generation of protein homology models, advanced data mining and analysis, and molecular dynamics calculations in interpretation of experimental data (structure and biology). You will have the opportunity to influence your own development and grow into a key role in an exciting and diverse discovery department.QualificationsAs a key member of a discovery research team, the ideal candidate has extensive experience in in silico structure-guided design and optimization of protein based therapies, and can combine structural and computational research with experimental data. The candidate holds a PhD and at least three years of documented post-doctoral experience in structural biology or molecular modelling. Experience could include one or more of the following: simulation and visualizing packages, homology modelling, protein-structure prediction, calculation of protein-protein energetics, and/or docking software. Research experience in large-scale data mining and analysis, bioinformatics, and using computational and/or statistical approaches is a plus. The candidate must be fluent in English, have excellent communication skills, a collaborative mind-set, and a passion for innovation.ContactFor further information about this position, please contact Hanne Grøn at (+45) 3079 0765Deadline15-Feb-2014