PhD position available at Imperial College
ri...@libero.it
The Chemical Biology (http://www.chemicalbiology.ac.uk/) Doctoral Training Centre is inviting applications for a 4 year EPSRC PhD studentship to commence in the 2009/2010 academic year.
Recent research has uncovered significant evidence that biological membranes may have an important role in regulating the behavior of drug molecules in vivo. A deeper understanding of the molecular basis of non specific binding, which arises when drug molecules bind to moieties other than their intended target, will facilitate the efficient design and selection of drugs acting at target proteins and improve our understanding of harmful toxicological processes such as phospholipidosis.
This project will investigate the structure-activity relationship for non specific binding by modelling the interaction between drug molecule candidates and phospholipid bilayers using a variety of ab initio and classical computational methods. Using these platforms you will test novel experimental theories on drug transport proposed at Imperial and GSK plc, and develop computational tools able to perform rapid screening of candidate drug molecules.
This project presents an exciting opportunity to acquire both a theoretical and practical understanding of computational methods and their application to clinically relevant systems. The successful applicant will work in close contact with biophysical experimental groups at Imperial College and GSK plc, and will have access to Imperial College extensive computational resources and PET tracer development facilities at the Clinical Imaging Centre, GSK, Hammersmith Hospital, for applied laboratory work.
The candidate should have an interest in molecular dynamics simulation and quantum mechanical computation. This position will involve software development, thus previous programming experience would be an advantage.
Eligibility: Applicants must have a good honours degree (2.1 or above) in a physical sciences subject. To be eligible for funding 'EU' and 'Overseas' applicants should have been resident in the UK for 3 or more years, and have no restrictions on their stay in the UK.
Post need to be filled by March 2009 (studies commence in Oct 2009).
Informal enquiries should be directed to: Dr Lula Rosso, MRC Clinical Science Centre, Imperial College London, lro...@csc.mrc.ac.uk .
Giorgio Volpe
biomedical research In ICFO is getting stronger. Many groups are working on biomedical or bioengineering applications of Optics and Photonicas, and a new group leader is starting in January as main responisble of the biomedical research in ICFO, translated: good moment for sendng CVs.
http://www.icfo.es/index.php?section=news1&lang=english&op=show_announcement&announcement_id=736
ICFO (The Institute of Photonic Sciences) is a relative new Institute based in barcelona. The main aim is to develope cutting-edge research in all the branches of Optics and Photonics Sciences in a young and active enviroment.
Check the website out: www.icfo.es
For applications: http://www.icfo.es/index.php?section=job_openings0&lang=english
Best,
Giorgio
p.s. do no hesitate in contacting me personally for any request..well..for any request that makes sense :-P
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